MRI measurement of airway soft tissues parameters in obese patients with and without obstructive sleep apnea

Congress:

ESCR 2014

Poster Number:

472

Type:

Scientific Poster

Keywords:

Head and neck, MR, Experimental investigations, Metabolic disorders

Authors:

E. Butorova, D. Ustyuzhanin, R. Bakhtiozin, M. Shariya; Moscow/RU

DOI:

DOI-Link:

https://dx.doi.org/

Fig. 1: Midsagittal MR image in patient with OSAS. MRI showed increase of tongue and...

Fig. 2: Axial MR image at retropalatal region in patient with OSAS. MRI showed increase...

Fig. 3: Axial MR image at retroglossal region in patient with OSAS. MRI showed an...

Fig. 4: Midsagittal MR image in obese patient without OSAS. MRI showed significantly...

Fig. 5: Axial MR image at retropalatal region in obese patient without OSAS. MRI showed...

Fig. 6: Axial MR image at retroglossal region in obese patient without OSAS. MRI showed...

Purpose

Currently, about 1.6 billion people in the world suffer from overweight. In most cases, patients with obesity identify obstructive sleep apnea (OSA). OSA is a condition characterized by the presence of snoring, periodically repeated partial or complete cessation of breathing during sleep, long enough to lead to lower levels of oxygen blood, coarse fragmentation of sleep and excessive daytime sleepiness. The diagnosis of OSA should be made if episodes of apnea last less than 10 seconds at least five times per hour. Excessive deposition of...

Methods and Materials

40 obese males (31 to 66 years) included in the study were divided into 2 groups. OSAS group included 20 patients with body-mass index (BMI) of 35.1±3.4 kg/m2 and apnea-hypopnea index (AHI) of 54±16. Control group included 20 patients with BMI of 32.0±2.6 and without OSAS (AHI of 2±1) or with light OSAS (AHI of 10±3). All patients underwent MRI using 3T scanner with measurement of the volume of the soft palate (VSP), the volume of tongue (VT), the volume of the lateral walls (VLW)...

Results

Patients with OSAS showed higher values of the volume of tongue (11.8±1.4 vs. 9.1±1.5 sm3), the volume of soft palate (2.7±0.4 vs. 2.1±0.3 sm3), the volume of lateral walls at RP region (3.5±0.8 vs. 3.0±0.6 sm3) and the volume of lateral walls at RG region (4.5±0.8 vs. 3.0±0.6 sm3) comparing with the control group, p<0.05 for all comparisons. In addition, patients with OSAS had lower values of the area of maximum airway constriction at the level of both RP (29±7 vs. 38±11 mm2) and RG...

Conclusion

Patients with obesity and OSAS have significantly higher volumes of airways soft tissues and lower area of maximum airway constriction comparing with obese patients without OSAS. These values can be used for OSAS early detection and assessment.

References

Chi L, Comyn FL, Mitra N, et al. Identification of craniofacial risk factors for obstructive sleep apnea using three-dimensional MRI. Eur Respir J 2011; 38:348-58. Sutherland K., R.J. Schwab et al. Facial Phenotyping by Quantitative Photography Reflects Craniofacial Morphology Measured on Magnetic Resonance Imaging in Icelandic Sleep Apnea Patients. SLEEP 2014; 37 (5):959-968. Moriwaki H, Inoue Y, Namba K, Suto Y, Chiba S, Moriyama H. Clinical significance of upper airway obstruction pattern during apneic episodes on ultrafast dynamic magnetic resonance imaging. Auris Nasus Larynx 2009;...