Purpose
MultidetectorCT angiography (CTA) and MR angiography (MRA) are well-established non-invasiveimagingtechniques for the differential diagnosis of pulmonary hypertension (PH).
CTA is considered as a gold standard for the diagnosis of pulmonaryembolism,
but this method is accompanied with the radiation exposure and use of iodinated contrast media.
MRA is a promising technique for the patients with PH.
Few studies to date have sought to determine the accuracy of MRA in diagnosis of chronicthromboembolic PH [1-5].
The purpose of our study was to evaluate the diagnostic value of...
Methods and Materials
Study populations consisted of 10 patients (m/f -3/7; mean age – 34.5+-3.1) with CTEPH.
CTA and MRA were performed in all the patients.
CTA was performed at64-row scanner using dual-energy mode (GSI technique).
The volume of the injected contrast medium was 40-7 0ml.
MRA was performed at1,5T MR system using 10-15 ml of contrast agent (1 mmol/ml).
3-5 ml of contrast agent injected at 2,5 ml/sec were used for the dynamic perfusion study.
After that CMR protocol for PH patents was implemented (SSFP and velocity-encoding...
Results
All the patients had CTEPH.
Patients data are presented in Table 1.
Table 1.
Patients data
Parameter
Value
Age (y.o.)
48.5±3.1
Mosaic attenuation pattern
10 (10)
Diameter of PA (mm)
33±7.6
PA/Ao diameter ratio
1,13±0,2
RV/LV diameter ratio
1,28±0,38
Collateral branches
7 (10)
PA occlusion (MRA)
55 (131) – 42 %
PA occlusion (CTA)
56 (131) - 42,
7 %
PA stenosis (MRA)
39 (131) - 29,7 %
PA stenosis (CTA)
48 (131) - 36,6 %
In total 131 segmental PA branches and 131 lung...
Conclusion
Pulmonary MRA has a high diagnostic value in the patients with CTEPH.
It is suitable for the assessment of pulmonary vessel morphology and pulmonary perfusion.
It can serve as an alternative to CTA.
References
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Value of high spatial and high temporal resolution magnetic resonance angiography for differentiation between idiopathic and thromboembolic pulmonary hypertension: initial results.
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Ley-Zaporozhan J,
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