Purpose
The ability of 64-slice cardiac computed tomography (CT) of the diagnostics of the Transposition of Great Arteries (TGA) was evaluated.
In this observational study we aimed to identify the sensitivity and specificity of CT as compared to echocardiography (ECHO) and invasive cardiac catheterization.
Methods and Materials
The retrospective study was performed at National Cardiac Surgery Center in Astana,
Kazakhstan,
within October 2011 - December 2015.
Eighty six patients with congenital heart disease expected to have TGA (age 0 - 30),
underwent conventional echocardiography and Cardiac CT using the 64-slice scanner with prospective ECG-synchronization and slice thickness reconstruction of 0,6 mm.
Some patients experienced invasive cardiac angiography.
In 80 patients TGA was proved,
including 61 D-TGA (79%) and 19 L-TGA (21%).
The potential of CT to detect and distinguish both types was...
Results
MSCT correctly detected TGA in 75 patients (93,75%) out of 80 in whom surgeon or invasive cardiac catheterization had identified TGA,
with a sensitivity,
specificity and negative predictive value of 100%.
5 cases of false negative results were received,
which were confirmed on ECHO subsequently.
Results of CT and ECHO matched in 69 (92%) patients.
Gender ratio presents predominance of 45 (60%) males over 30 (40%) females.
61 patients (79%) had D-TGA (21%) and 14 patients had L-TGA only.
The majority of patients have been...
Conclusion
64-slice Cardiac CT performs as well as echocardiography in the majority of children who have TGA.
Sensitivity of 93,75% and specificity of 99.34%,
shows a fairly good level.
CT also provides detailed information on the types of TGA and another CHD.
However,
to increase the proportion of correct diagnostic results,
CT and Echo should complement one another.