Purpose
Pancreatic carcinoma has a very poor prognosis because of its nature for early local and distant spread.
Especially,
pancreatic body and tail carcinoma is usually found at a later stage,
accompanying the carcinoma invasion to major vessels and to the retroperitoneum.
In Western countries,
the respectability of the pancreatic body and tail carcinoma and the 5-year survaival is estimated at both about 10% 1,
2).
In pancreatic body and tail carcinoma,
the “peripancreatic radiating thick-strands”,
deriving from primary lesion and is associated with increased CT...
Methods and Materials
We retrospectively evaluated the contrast-enhanced MDCT images of 17 patients with pancreatic body and tail carcinoma who underwent surgical operation from January 2005 to August 2010.
<Subjects>
12 men and 5 women (ranging in age from 57 to 85 years,
with a mean age of 71.6 years)
・tumor site: body of pancreas (5 case),
body-tail of pancreas (9 cases),
tail of pancreas (3 cases)
*Carcinomas located in or extended to the pancreatic head were excluded.
・Pathological diagnosis : tubular adenocarcinoma in all cases
・TS (tumor...
Results
1. Presence of “peripancreatic radiating thick-stands” on MDCT
a) Frequency
Positive finding in 13(76%) of 17 cases
b) Frequency in each 4 area (Fig.2)
(A: abdominal aorta,IVC: inferior vena cava,PV: portal vein,S: superior mesenteric artery)
The “peripancreatic radiating thick-strands” was seen at the anterior area in nine cases (69%),
the posterior in eight cases (62%),
the superior area in 10 cases (77%),
and at the posterior area in 13 cases (100%),
respectively.
The difference in detectability was mainly due to the amount of adipose tissues...
Conclusion
““Peripancreatic radiating thick-strands”” seen on MDCT in pancreatic body and tail carcinoma reflects the extrapancreatic carcinoma invasion with marked fibrotic thickening of adipose tissue septa,
including micro-vessels.
This CT finding is important to decide the preoperative staging,
and to judge the necessity for chemotherapy.
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Pancreatic Carcinoma Cells Induce Fibrosis by Stimulating Proliferation and Matrix Synthesis of Stellate Cells.
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Omary MB,
et al.
The pancreatic stellate cell: a star on...
Personal Information
Shunro Matsumoto,
MD
Oita university faculty of Medicine,
Department of Radiology
879-5593 Idaigaoka 1-1 Hasama-machi yufu-shi Oita JAPAN
Phone: 81-97-586-5934
Fax: 81-97-586-0025
E-mail:
[email protected]