Purpose
Prostate cancer (P ca)is the most common cancer diagnosis among North American and European men and causes significant morbidity and mortality.
Recent advances in management of P ca like Active surveillance and focal therapies including Intensity Modulated Radiation Therapy ( IMRT),
Cryotherapy and High-Intensity Focused Ultrasound (HIFU)have made accurate tumour detection,
staging and delineation of tumour extent all the more important in current practice .
1)The purpose of our study is to assess the additional value of Diffusion Weighted Imaging (DWI) in the detection ,...
Methods and Materials
All prostate MRI scans performed over aone year period(1st March 2011 to 1st March 2012) were included.
Scans were performed on a 1.5 T Phillips magnet with a standard pelvic coil.
Standard MRI sequences included a T1W axial,
T2W axial,
coronal and sagittal sequences through the pelvis .
Diffusion weighted images were acquired usingb0,
b100,
b400 and b800 gradient.
Inbuilt Phillips software provided a corresponding ADC map using a mono-exponential gradient.
All scans were double read by a panel of Radiologist (AC,
CG ,
AJ)...
Results
206 patients underwent MRI of the prostate in the study period.
6 patients were excluded due to non-diagnostic MR images.
127 patients accounting for 62 % had additional finding on DWI that were not obvious on standard MRI sequences.
These are categorised and discussed as below:
Tumour detection:
Anterior prostate tumors are difficult to image and biopsy on TRUS .
These contribute largely to the false negative rate of TRUS guided biopsy which has been reported to be between 11 and 25%.
Benign prostatic hypertrophy...
Conclusion
Diffusion weighted imaging is a robust technique with only 3 % of patients having a non-diagnostic examination.
No specialist software is requiredasDWIis widely usedin neuroradiology departments and images are acquired in a short span to time.
In our experience 62% of patients had significant additional finding on DWI.DWI proved beneficialin all aspects of the patient journey,
ranging from tumourdetection,
staging,
treatment planning and surveillance.
We recognise there is a learning curve with this technique and there arevariations in image interpretation.
Our review demonstrated an interobserver...
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