Learning objectives
1.
To assess the radiological MRI findings of diseases affecting the corpus callosum.
2.
To review and illustrate these diseases in order to establish the correct differential diagnosis.
Background
The corpus callosum plays a fundamental role in the transfer of information and integration between the hemispheres.
Different pathologies affect the corpus callosum,
including in large groups: tumoural diseases,
inflammatory-demyelinising events,
vascular processes,
traumatic injuries,
endocrine and metabolic causes,
infectious agents and toxic insults,
among others.
Radiologist should know their imaging features in order to establish the correct differential diagnosis.
This exhibit reviews the radiological MRI findings in patients scanned at our centre demonstrating involvement of the corpus callosum.
Imaging findings OR Procedure details
The corpus callosum is the principal supratentorial cerebral commissure (white matter tract) connecting symmetrical areas of cerebral hemispheres (between the parietal lobes,
posterior frontal and superior temporal regions).
It is divided in four segments: rostrum,
genu,
body and splenium.
It forms during embryogenesis,
between the 8th and 20th week of life.
It develops in an anterior-posterior direction except for the rostrum,
which is the last to form.
It contains very compacted myelinated axonal fibres,
which hinder the diffusion of interstitial oedema and tumour extension.
However,...
Conclusion
This exhibit has revised and illustrated different pathologies affecting the corpus callosum based on radiological MRI findings,
in order to establish a correct differential diagnosis.
References
- Bourekas EC et al.
Lesions of the corpus callosum: MR imaging and Differential considerations in adults and children.
AJR 2002; 179: 251-7.
- B Battal et al.
Corpus callosum: Normal imaging appearance,
variants and pathologic conditions.
Journal of Medical Imaging and radiative Oncology 2010,
54: 541-9.
- Galluci M et at.
Reversible focal splenial lesions.
Neuroradiology 2007,
49: 541-544.
- Moritán T et at.
Diffusion-Weighted Imaging of Acute Brain Injury excitotoxic.
AJNR Am J Neuroradiol 2005; 26:216-228.
- Sam Soo Kim et at.
Focal...
