Whole-body Diffusion-Weighted MR imaging: evaluation and anatomic distribution of patients for bone metastases

Congress:

ECR 2013

Poster Number:

C-1923

Type:

Scientific Exhibit

Keywords:

Bones, Oncology, MR, MR-Functional imaging, Imaging sequences

Authors:

R. Del Vescovo, G. Frauenfelder, F. Giurazza, R. L. Cazzato, R. F. Grasso, B. Beomonte Zobel; Rome/IT

DOI:

10.1594/ecr2013/C-1923

DOI-Link:

https://dx.doi.org/10.1594/ecr2013/C-1923

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Purpose

To compare the results of whole-body Diffusion-weighted magnetic resonance (DW-MR) imaging with staging based on computed tomographic (CT) and nuclear scintigraphic results as standard of reference.

Methods and Materials

Fourteen patients with known malignant tumors were included in the study. The thorax and the abdomen were imaged by using breath-hold diffusion-weighted imaging (DWI) and T1-weighted imaging sequences in the coronal plane. Location and size of osseous metastases were documented by two experienced radiologists. Whole-body DW-MR imaging findings were compared with results obtained at skeletal scintigraphy and CT.

Results

The mean examination time for whole-body DW-MR imaging was 25.5 minutes. All bone metastases regardless of the size could be identified with whole-body DW-MR imaging; MR imaging depicted more bone metastasis than CT. Skeletal scintigraphy depicted osseous metastases in 23 patients (with greater sensitivity to the lower limb), whereas whole-body DW-MR imaging revealed osseous metastases in 25 patients (with greater sensitivity to the spine). DW-MR do not show good results for rib cage metastasis detection. The additional osseous metastases seen with MR imaging were confirmed...

Conclusion

Whole-body DW-MR imaging was more sensitive in the detection osseous metastases than were the reference techniques.

References

Huisman TA. Diffusion-weighted imaging: basic concepts and application in cerebral stroke and head trauma. Eur Radiol 2003; 13(10):2283-2297. Koh DM, Collins DJ. Diffusion-weighted MRI in the body: applications and challenges in oncology. AJR Am J Roentgenol 2007; 188:1622-1635. Li S, Sun F, Jin ZY, Xue HD, Li ML. Whole-body diffusion-weighted imaging: technical improvement and preliminary results. J Magn Reson Imaging 2007; 26:1139-1144. Balliu E, Boada M, Peláez I, et al. Comparative study of wholebody MRI and bone scintigraphy for the detection of bone metastases. Clin...

Personal Information

Dr. Riccardo Del Vescovo, MD Department of Radiology University Campus Bio-Medico School of Medicine Via Alvaro del Portillo 200, 00128 Rome Cell.:+39-338-1111915 e-mail: [email protected]