Spectrum of inflammatory demyelinating diseases

Congress:

ECR 2013

Poster Number:

C-1709

Type:

Educational Exhibit

Keywords:

Neuroradiology brain, Neuroradiology spine, MR, CT-High Resolution, MR-Diffusion/Perfusion, Imaging sequences, Treatment effects, Metabolic disorders, Education and training

Authors:

O. Addou¹, B. Alami¹, S. Ballakhdar², M. Maaroufi¹, M. Boubou¹, S. Tizniti¹; ¹Fes/MA, ²Fes, Fes/MA

DOI:

10.1594/ecr2013/C-1709

DOI-Link:

https://dx.doi.org/10.1594/ecr2013/C-1709

Fig. 1: The inflammatory-demyelinating disease of the central nervous system (CNS) in...

Fig. 2: Axial(a,b) and coronal(c)T2-weighted images showing typical ovoid...

Fig. 3: Axial FLAIR images revealing periventricular hyperintense MS lesions and...

Learning objectives

The purpose of our study was to review the role of imaging in the diagnosis of inflammatory demyelinating disorders and to become familiar with differential diagnosis of these diseases.

Background

We report a retrospective study that evaluates 91 cases with inflammatory-demyelinating disease of the central nervous system (CNS), seen from January 2009 to March 2012. Some patients underwent cerebral CT scanning (n=35) and all of them undergo cerebral MR imaging (n=91). Semiological patterns, cerebrospinal fluid (CSF) analysis and temporo-spatial evolution of the lesion led to the diagnosis.

Imaging findings OR Procedure details

The inflammatory demyelinating diseases identified were as follows: Multiple sclerosis (n = 40) with one case of pseudotumor cerebri syndrome (n = 1); Devic's disease or neuromyelitis optica (n = 2), acute disseminated encephalomyelitis (n = 8), Lyme disease (n = 1); neuro-Behçet's disease (n = 16); lupus erythematosus (n = 3); Gougerot Sjogren (n = 1); neurosarcoidosis (n = 2). (Fig 1) 1- Multiple sclerosis: Multiple sclerosis (MS) is the most common chronic inflammatory demyelinating disease affecting the central nervous system (CNS) of young...

Conclusion

Good knowledge of the MRI radiological findings of the inflammatory demyelinating diseases, allows a better approaches to the diagnosis of these complex diseases.

References

1. Noseworthy JH , Lucchinetti C , Rodriguez M , Weinshenker BG . Multiple sclerosis . N Engl J Med 2000 ; 343 ( 13 ): 938 – 952 . 2. Swanton JK , Rovira A , Tintore M , et al . MRI criteria for multiple sclerosis in patients presenting with clinically isolated syndromes: a multicentre retrospective study. Lancet Neurol 2007; 6 (8): 677 – 686. 3. Barkhof, F. “MRI in multiple sclerosis: correlation with expanded disability status scale,”1999. Mult Scler 5(4): 283-6. 4....