Purpose
The aim of study is to evaluate the effectiveness of the ischemic stroke treatment with the use of invasive radiological techniques ,
targeted thrombolysis and mechanical thrombectomy.
This study was conducted to demonstrate which of the endovascular aforementioned methods is more effective.
It shows the impact of endovascular treatment of ischemic stroke affects the clinical status of patients and which are the most frequently occluded arteries.
Methods and Materials
Materials:
This retrospective study involved a group of 19 patients hospitalized in SP CSK im.
prof.
K.
Gibińskiego SUM in Katowice,
who in 2005-2012 were treated with targeted thrombolysis and mechanical thrombectomy.
The average age of patients with ischemic stroke was 60.36 years (with a range of 26-84 years) (Table 1).
Neurological examination (assessed using the National Institutes of Health Stroke Scale [NIHSS]) was performed before and after surgery and at discharge from the ward.
Qualifications protocol:
In order to exclude patients with hemorrhagic stroke,...
Results
25 endovascular procedures were performed: 13 targeted thrombolysis and 12 mechanical thrombectomy.
During thrombolysis ReoPro (Abciximab) was used twice,
the rt-PA 11 times.
Mechanical thrombectomy was performed using a 7 Penumbra sets,
5 Solitaire FR sets.
Two times combination therapy (targeted thrombolysis and mechanical thrombectomy) was used (Table 3).
In three cases of the vascular spasm papaverine was applied.
Obstruction occurred most frequently in the middle cerebral artery (36%),
basilar artery (24%),
vertebral artery (12%) and internal carotid artery (12%) (Table 4).
We evaluated 19...
Conclusion
The research performed has shown that endovascular techniques are effective and safe in the treatment of ischemic stroke.
Targeted thrombolysis is more effective than mechanical thrombectomy.
Patients who were treated endovasculary improved significantly.
The middle cerebral artery was the most common site of obstruction.
The main limitation of the objectivity of the results was the small number of patients,
so our conclusions regarding the safety and efficacy of these methods do not reflect the condition of the population.
Currently there is no doubt that a...
References
1.
Jan Baron i Joanna Pilch-Kowalczyk,
Wprowadzenie do diagnostyki obrazowej,
Wydanie: II,ISBN: 978-83-7509-173-1
2.
Castro-Afonso LH,Abud TG,Pontes-Neto OM,Monsignore LM,Nakiri GS,Cougo-Pinto PT,Oliveira Ld,Santos DD,Dias FA,Fábio SC,Coletto FA,Abud DG,
Mechanical thrombectomy with solitaire stent retrieval for acute ischemic stroke in a Brazilian population,
Clinics (Sao Paulo).2012 Dec;67(12):1379-86.
[PubMed]
3.
Bae GS,Kwon HJ,Kang CW,Choi SW,Kim SH,Koh HS,
Mechanical thrombectomy using a solitaire stent in acute ischemic stroke; initial experience in 40 patients,
J Cerebrovasc Endovasc Neurosurg.2012 Sep;14(3):164-9.
[PubMed]
4.
Piotr Sobolewski,
Review of invasive endovascular methods of treatment...
Personal Information
Daniel Knap,
PhD,Medical University of Silesia,
Katowice,
Poland;
Tomasz Kirmes,
student,
Medical University of Silesia,
Katowice,
Poland;
[email protected]
Maciej Honkowicz,student,
Medical University of Silesia,
Katowice,
Poland;
[email protected]
Marcin Koroński,student,
Medical University of Silesia,
Katowice,
Poland;
Marzena Kysiak,student,
Medical University of Silesia,
Katowice,
Poland;
Mateusz Bukański,student,
Medical University of Silesia,
Katowice,
Poland;
Jan Baron,
PhD,Medical University of Silesia,
Katowice,
Poland;