Learning objectives
Fungal infections are widespread in the environment.
The most common fungus infecting the liver is the Candida species,
however,
this infection is diagnosed antemortem in few cases [1].
Management of fungal hepatic abscesses is not well established but includes drainage of the abscess and early antimycotic therapy.
Early diagnosis is critical for optimal patient management and clearly linked to better survival rates [1].
The aim of our study was to illustrate the radiological findings of candidal liver abscesses,
to describe the value of Ultrasound (US),...
Background
Candida infection is an emerging important nosocomial infection.
Immunosuppressive therapy,
the use of broad-spectrum antibiotics and other predisposing factors such as long-term parenteral nutrition or diabetes mellitus,
are responsible for an increasing number of immune-compromised patients and consequent opportunistic infections [2]. Particularly invasive fungal infection and hepatic abscesses are a well-known complication of prolonged neutropenia in patients who are undergoing treatment for hematologic malignancies [3].
The most commonly reported symptoms are fever unresponsive to antibiotic treatment and abdominal pain.
Patients may also present with nausea,...
Imaging findings OR Procedure details
Ultrasound and computed tomography are the first line imaging modalities; in the next step,
MRI is useful in the detection of small differences in tissue composition in fungal infection due to multiplanar capability and excellent contrast resolution.
Candidal liver disease is usually characterize by microabscess and granulomas,
in contrast large abscess are rare [4].
Four patterns of US findings of liver fungal abscesses have been observed,
correlating to the stage of the disease: the most common pattern is the least specific appearance of liver abscesses...
Conclusion
A definitive diagnosis of Candidal liver abscess is difficult to make in order to different and generally not specific radiological imaging appearances; US and CT are the first-line methods in the identification and characterization of abscesses while MRI is useful in the follow up of the patient during treatment.
References
Metser U,
Haider MA,
Dill-Macky M,
Atri M,
Lockwood G,
Minden M.
Fungal liver infection in immunocompromised patients: depiction with multiphasic contrast-enhanced helical CT.
Radiology.
2005 Apr;235(1):97-10.
Lima R,
Shams W,
Kalra S,
Borthwick T.
Candida glabrata liver abscess and fungemia complicating severe calculus cholecystitis in an immunocompetent nondiabetic host.
South Med J.
2010 Mar;103(3):245-7.
doi: 10.1097/SMJ.0b013e3181c9803b.
J.
Cantu.
Hepatosplenic Candidiasis in Patients with Acute Leukemia.
The Internet Journal of Emergency and Intensive Care Medicine.
2005 Volume 8 Number 2.
doi: 10.5580/2c6.
Mortelé KJ,
Segatto...