Background In the diagnosis of malignant tumors of the musculoskeletal system a major role plays the methods that allow to visualize the anatomical location and the structure of the tumor, establish it relationship to the surrounding tissues and organs. This primarily refers to the X-ray method, MRI, and in some cases - the ultrasound [1-5]. However, in practice, may be up to 60% of the errors in the initial recognition of malignant bone lesions. Despite the fact that the known already of the pathogenesis of...

We analyzed data of integrated ultrasound investigation in 49 children and adolescents aged 7-17 years with prospectively confirmed diagnosis of osteogenic sarcoma (28) and Ewing's sarcoma (21). In all cases process was localized in the tubular bones of the lower extremities. Patients with SE and OS received chemotherapy according to protocols EURO-EWING-99 and COSS-96, EURAMOS respectively. In comparison group were 42 children of similar age with benign tumors and tumor-like conditions (osteoid osteoma, cyst, fibrous dysplasia, osteochondroma, calcified hematoma, venous dysplasia). For all were estimated:...

There was the predominance of the size of the affected area of malignant neoplasms compared with benign. The average volume of of malignant neoplasms was 252±240cm³. The soft-tissue component of bone sarcomas was presented as heterogeneous echostructure (Fig. 1). In most cases it was tumor outgoing from the bone. And bone was with altered in varying degrees of cortical integrity tissue (Fig. 2, 3).Thus, common features of malignant bone tumors in most cases: irregular shape, fuzzy contours, low acoustic density, heterogenity of echostructure. In 32%...

By multi modalities ultrasound were obtained by quantitative and qualitative characteristics bone sarcomas in children and adolescents. Pathological mechanisms of hemodynamic support of the affected limb may include systemic increase in CO, regional changes in vascular tone and against this background - the redistribution of certain volumes of blood between from healthy to the affected limbs. Comparative analysis of quantitative characteristics proximal blood flow in both healthy and the affected limb helps effectively distinguish between sarcomas and benign tumors of bones. It is established that...

Hwang S.,PanicekD.M. The Evolution of Musculoskeletal Tumor Imaging // Radiol. Clin. North. Am. 2009. V. 47, №3, P. 435- 453. Van der Woude H.J., Vanderschueren G. Ultrasound in musculoskeletal tumors with emphasis on its role in tumor follow up // Radiol. Clin. North. Am. 1999. V. 37, № 4. P. 753- 766. Saifuddin A., Burnett S. J., Mitchell R. Pictorial review: ultrasonography of primary bone tumors // Clin Radiol. 1998. V.53(4). P. 239- 246. Bodner G., Schocke M.F., Rachbauer F. et al. Differentiation of Malignant...

As a doctor ultrasound diagnostics and physiologist I am working in the area of pediatric oncology in National Scientific and Practical Center of Children's Oncology, Hematology and Immunology Republic of Belarus since 1997. I am interested in non invasive research blood supply of the tumors and modelling of its growth. With my collegues we trying to do in Belarus, something similar, but we would like to give more mathematical justification of our work. Initially, it was a modelling of regional hemodynamics in children with congenital...