Aims and objectives
- Evaluate the influence of an automatic software called Personalized Patient Protocol Technology or P3T® Medrad-Europe used for adjusting contrast dose by weight.
- Determine their influence on the image quality obtained in abdomen Computed Tomography (CT) scan.
[1-3] Fig. 2 Fig. 3
Methods and materials
Patients: Development of the study:
Between August 7th and September 3rd 2013,
237 patients (132 males and 105 females),
mean aged of 61.3 years (SD 1.4) and mean weight of 74.1 kg (SD 15.27) were refered for follow up of their oncology disease. Fig. 4
The amount of contrast medium was calculated by P3T system according to weight (group B).
Each abdomen CT was compared to another in the same patient and the same standard protocol performed with fixed contrast medium dose of 120 ml...
Results
Contrast dose
Contrast dose used in group A was higher (120 ml) than in group B (109.3 ml) (SD 16.9),
reducing an average of 10.7 ml of contrast medium.
After statistical analysis,
significant differences were found between both groups (p = 0.001). Fig. 14
Stratifying according to the weight: In group B,
patients weighing <80 kg decrease significantly the contrast dose 19.2 ml (the contrast average dose in group A was 120 ml and in group B 100.8 ml (SD 11.9)) (p = 0.001),
while...
Conclusion
The use of P3T:
- Decreases significantly the contrast dose in patients weighing < 80 kg.
- Increases significantly the contrast dose in patients weighing ≥ 80 kg.
- Means no deterioration in image quality. Fig. 19
References
1- Radiation Dose Optimization and Thoracic Computed Tomography.
Singh S,
Kalra M.K,
Khawaja R.D.A,
Padole A,
Pourjabbar S,
Lira D et al.
Radiol Clin N Am.
2014:52; 1–15.
2- Fleischmann D,
Kamaya A.
Optimal vascular and parenchymal contrast enhancement: the current state of the art.
Radiol Clin North Am.
2009;47:13-26.
3- Arana E,
Martí-Bonmatí L,
Tobarra E,
Sierra C.
Cost reduction in abdominal CT by weight-adjusted dose.Eur J Radiol.
2009;70:507-11.
4- Nakayama Y,
Awai K,
Funama Y,
Hatemura M,
Imuta M,
Nakaura T,
et all....