Learning objectives
To emphasize the role of Magnetic Resonance Enterography (MRE) in diagnostic algorithm in Crohn’s Disease (CD).
To illustrate imaging signs of active and chronic bowel disease as well as its complications,
both mural and extramural,
also in reference to structured reporting.
To briefly discuss MRE imaging protocolin reference to the one applied at our Department.
Background
Crohn’s disease (CD) is an idiopathic chronic inflammatory disease of the gastrointestinal tract often encountered in young adults with tendency to frequent relapses.
CD may affect any part of the digestive tract.
However,
the small intestine,
in particular the terminal ileum,
is most commonly affected.
Disease is characterized by so called skip-lesions - areas of inflammation separated with regions of normal mucosa.
Inflammation most commonly manifests as ulceration,
varying from superficial lesions to deep linear ulcers.
As it is often a transmural process complications such...
Findings and procedure details
We have retrospectively reviewed MRE examinations performed in years 2012-2014 at our Department and further selected those of 128 patients with CD confirmed with histopathological examination.
All examinations have been performed in a 1.5-T scanner,
using a phased array surface coil.
The recipe for optimal MRE includes adequate bowel distention,
fast sequences,
use of a large field-of-view surface coil and administration of an intravenous contrast agent.
Adequate bowel distention. Several types of enteric contrast agents (CA) may be used to study the small bowel with...
Conclusion
Crohn’s disease (CD) is an idiopathic chronic inflammatory disease of the gastrointestinal tract often encountered in young adults with tendency to frequent relapses.
MRE is becoming the modality of choice in evaluation of Crohn’s disease.
It allows safe and noninvasive diagnostic tool without exposure to ionizing radiation as well as help in treatment planning and follow-up.
Interpretation of MRE images requires familiarity with the imaging signs of active and chronic bowel inflammation.
It can help assess the activity of the disease,
demonstrate both mural and...
References
Allen BC,
Leyendecker JR.
MR enterography for assessment and management of small bowel Crohn disease.
Radiol Clin North Am.
2014 Jul;52(4):799-810.
Pola S,
Santillan C,
Levesque BG,
Feagan BG,
Sandborn WJ.
An overview of magnetic resonance enterography for Crohn's disease.
Dig Dis Sci.
2014 Sep;59(9):2040-9.
Amitai MM,
Ben-Horin S,
Eliakim R,
Kopylov U.
Magnetic resonance enterography in Crohn's disease: a guide to common imaging manifestations for the IBD physician.
J Crohns Colitis.
2013 Sep 1;7(8):603-15.
Giles E,
Barclay AR,
Chippington S,
Wilson DC.
Systematic review:...