T-SLIP (Time spatial labeling inversion pulse) is a relatively new and promising method for non-contrast MR- angiography . Time-SLIP is a non-contrast MRI technique that provides bright blood in vessels. Time-SLIP is a variant of an arterial spin labeling (ASL) technique and utilizes a selective suppressed pulse for label the blood as it flows into or out of an imaging region. Non saturated blood inflow into region suppressed by Inversion Pulse and demonstrated high signal of blood pool. The protocol was introduced in our clinic...

T-SLIP sequence allows scanning almost all anatomical areas of the human body in vascular diagnostics - both large vessels, such as neck vessels [1], chest vessels [2], abdomen vessels (including portal system [3]), hepatic artery [4], renal artery [5], and vessels of the limbs, include small peripheral vessels [6]. All studies were performed on an 1,5 Tesla MR unit (Toshiba Excel ART Vantage, Japan), sequence battery included T1, T2 (including Fat Sat), T2* (neck region) weighted images, 3D TOF angiography (neck region), T-SLIP sequence: BBTI...

Fig.1 a,b shows images (MIP postprocessing) taken on a 50 years old male patient with an additional S shaped bend of the left internal carotid artery, a) – T-SLIP, b) – 3D TOF images. Tortuosity visualized better on 3D TOF images despite the higher noise. Relative contrast and contrast /noise ratio were compared to 3D TOF and T-SLIP modes are presented in Fig.2. For T-SLIP (vs 3DTOF) relative contrast (Fig.2 a) of above 16%, the ratio of the contrast /noise ratio (Fig.2 b) is above...

- Noninvasive T-SLIP angiography is a highly efficient scanning method which can be used in clinical practice for providing additional functional information. Compared with the 3D-TOF MR angiography, it possesses better characteristics of image: relative contrast (above 16%) and contrast /noise ratio (above 29%). - The most informative results of using T-SLIP are obtained when visualizing the large vessels, which should be considered when choosing patients for the investigation. - At the same time, this method has specific limitations: it is impossible to use the...

Mr. Vinokurov Anton S. Pirogov Russian National Research Medical University (RNRMU), Moscow, RF. [email protected] Dr. Petraikin Alexey Vl. MD, PhD Pirogov Russian NationalResearch Medical University (Research Institute of cerebrovascular disease and stroke), Moscow City Clinic 134, Moscow, RF. [email protected] Dr. Sidorin Sergey V. MD Moscow City Clinic 134, Moscow, RF. [email protected]

1) W.W. Orrison Jr, E.J. Kelly, D. Moreau, C.J. Roach, E.H. Hanson , Optimization of Non-Contrast Enhanced Time-SLIP for Carotid Artery Imaging, Proc. Intl. Soc. Mag. Reson. Med. 19 (2011) 2) T. Miyazaki, Y. Kawabata, R. Watanabe, K. Takahashi, S. Terada, S. Shimizu, Description of non-contrast-enhanced pulmonary vein with using the Time-Slip method , ECR 2011 / C-0825, http://dx.doi.org/10.1594/ecr2011/C-0825. 3) X. Wang, H.-D. Xue, Z. Jin, Non-contrast-enhanced MR portography with time-spatial labeling inversion pulses, ECR 2012 / C-1354, http://dx.doi.org/10.1594/ecr2012/C-1354 4) T. Yoshikawa, N. Aoyama, K....