Learning objectives
This poster will provide an overview of a few unusual types of breast cancer.
Describe the main features of image,
patient demographics,
clinical characteristics and some histopathological findings may suggest that the findings are unusual breast cancer.
Background
Invasive ductal carcinoma not otherwise specified (IDC-NOS) and ductal carcinoma in situ (DCIS) account for about 85% of breast cancers.
The remaining 15% of breast cancers are other types of malignant neoplasm.
Unusual breast neoplasms may be broadly divided into:
Invasive lobular carcinoma (ILC)
Tubulolobular carcinoma
Well-differentiated subtypes of invasive ductal carcinoma (IDC)
Cancers of stromal origin
Metastatic neoplasms.
Invasive lobular carcinoma infiltrates the breast in thin sheets of cells similar to a spiderweb,
typically resulting in thickening at clinical examination,
architectural
distortion without a...
Findings and procedure details
INVASIVE LOBULAR CARCINOMA (Fig.
1,2)
Terminology
Invasive cancer characterized by loss of normal cell adhesion; invades as individual cells or single-file cell columns.
Clinical Issues
Accounts for 6%–9% of breast cancers; 10-15% of all invasive breast cancer
Palpable mass or vague palpable area thickening,
shrinking breast,
skin/nipple retraction.
Matched by stage and grade,
prognosis is similar to that of IDC NOS.
Imaging
Overrepresented among missed or delayed diagnoses
Mammography (MMG): Spiculated mass (most common),
new focal asymmetry,
may be one-view only; Architectural distortion,
shrinking breast....
Conclusion
Unusual breast neoplasms may be broadly divided into invasive lobular carcinoma,
tubulolobular carcinoma,
well-differentiated subtypes of invasive ductal carcinoma,
cancers of stromal origin,
and metastatic neoplasms.
The well-differentiated subtypes of IDC have a better prognosis than does IDC not otherwise specified.
They are characterized by slow growth (except medullary carcinoma) and a relatively circumscribed appearance at mammography (except for tubular carcinoma,
which appears spiculated).
Mucinous carcinoma has low density on a mammogram and high signal intensity on T2-weighted MR images due to high mucin content....
References
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Unusual Breast Cancers: Useful Clues to Expanding the Differential Diagnosis.
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Vol 242:Number 3,March...