Learning objectives Because of the varied presentation of the celiac disease CT plays critical role not only in establishing diagnosis but also helps in excluding other conditions with similar clinical presentation. Improved CT resolution and newer techniques (CT enteroclysis & CT enterography) now permits better depiction of the small bowel, colon, and mesenteric lymph nodes, all of which are affected by celiac disease. Detection of celiac disease with CT will allow early initiation of treatment to prevent the morbidity associated with a delay in diagnosis....

Introduction Celiac disease also termed as non-tropical sprue is a malabsorptive gastroenteropathy caused by small intestinal autoimmune response to gluten in genetically predisposed individuals. Gluten proteins are found in wheat, rye, barley, and certain other grains. It is a chronic disease characterized by mucosal lesions of the small bowel that impair nutrient absorption. Hence it should always be considered as the possible underlying etiology in cases of Iron deficiency anemia of uncertain cause. Pathology and pathogenesis Site of pathology The small bowel mucosa (Submucosa, Muscularis...

Materials and Methods We prospectively studied two adult male patients(34 and 17 years) who attended department of radiology, Vydehi medical college and research center, Bangalore. Both the patients underwent MDCT enterography examination followed by endoscopic biopsy of the duodenal mucosa and histopathological examination. MDCT Technique Patient preparation: The patients were asked to take low residue diet, ample fluids and laxatives on the day prior to the examination and nothing by mouth on the day of examination. Preprocedural: One ampoule of metoclopramide was given intravenously 60...

Celiac disease is now recognized as a common condition with significant long-term morbidity and increased risk of mortality. However, most cases remain undiagnosed. Early recognition and treatment virtually eliminate the morbidity of celiac disease and the risk of mortality. A pattern of small bowel and colonic findings with mesenteric lymph node prominence at MDCT should suggest the diagnosis of celiac disease. Knowledge of the pathophysiology of celiac disease helps one comprehend the spectrum of imaging findings.

Dr Rohini Avantsa, MD. Sectional ImagingDivision, Department of radiology, Vydehi institute of medical sciences, Bangalore, India. [email protected] Dr Prachi Kala, MD. Sectional ImagingDivision, Department of radiology, Vydehi institute of medical sciences, Bangalore, India. Dr M.D.Srikar Inuganti, Resident, Department of radiology, Vydehi institute of medical sciences, Bangalore, India.

1. Francis J. Scholz, MD. Spencer C. Behr, MD. CT Findings in Adult Celiac Disease. RadioGraphics 2011; 31:977–992 2. Tomei E, Marini M, Messineo D, et al. Computed tomography of the small bowel in adult celiac disease: the jejunoileal fold pattern reversal. Eur Radiol 2000;10 : 119-122 3. Moser PP, Smith JK. CT findings of increased splanchnic circulation in a case of celiac sprue. Abdom Imaging 2004;29(1):15–17. 4. Reddy D, Salomon C, Demos TC, Cosar E. Mesenteric lymph node cavitation in celiac disease. AJR Am...