Value of 1H spectroscopy 3T MR imaging in breast lesions in addition to BIRADS MR findings and DWI: a preliminary report

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Congress:

ECR 2015

Poster Number:

B-1156

Type:

Scientific Paper

Keywords:

Breast, MR-Spectroscopy, MR-Diffusion/Perfusion, MR, Computer Applications-Detection, diagnosis, Cancer

Authors:

R. Asadov, M. E. Aribal, A. Ramazan, M. U. Ugurlu, H. Kaya; Istanbul/TR

DOI:

10.1594/ecr2015/B-1156

DOI-Link:

https://dx.doi.org/10.1594/ecr2015/B-1156

Fig. 1

Fig. 2: BIRADS MR

Fig. 3: Roc curve for measurments of ADC value

Fig. 4: Roc curve for measurments of total cholin peak

Purpose

The value of 1H spectroscopy MR was evaluated in addition to MR BIRADS findings and DWI.

Methods and materials

Fortynine patient with 54 lesions were evaluated with 3T MR. Morphologic findings according to MR BIRADS, 1H spectroscopy values and ADC measurements were evaluated blindly. This prospective study was statisticaly analyzed with Ki-Square and Fisher Exact test. For ADC and Spect measurements ROC curve analyses was used. The histopathologic diagnosis of lesions was accepted as the gold standard.

Results

MR morphological and dynamic findings as irregular shape, spiculated and illdefined margins, type 2 and 3 enhancement pattern were accepted as signs of malignancy. The AUC for spectroscopy and ADC was 0.850 and 0.740 respectively (p<0.001). Cutoff values for ADC and Spectroscopy choline level were determined as 1.118 and 1.3 respectively. When any three of; shape, margin, enhancement pattern, ADC or Spectroscopy were taken in consideration for malignancy; sensitivity, specificity, accuracy and NPV were 96.7%, 79.2%, 88.9%, and 95% respectively. When any one of BIRADS...

Conclusion

Spectroscopy and ADC measurements add value to the routine breast MRI evaluation that benignbreast biopsies can be avoided and malignant lesion detection sensitivity can be increased.

Personal information

References

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