Aims and objectives
General objective
To determine the bone density profile evaluated by computed tomography and DXA,
associated to risk factors for breast cancer.
Specific objectives
To describe the levels cut off bone density values in a group of patients with breast cancer using Hounsfield units for:
Normal bone density
Osteoporosis and/or osteopenia
To demonstrate the correlation between the bone density profile by computed tomography and the patient's’ age
To describe the correlation between the bone density profile by computed tomography and the BMI
To describe the sensibility...
Methods and materials
· Type of study
An observational and prolective investigation was realized.
· Group and sample size
470 patients’ medical records (Centro de Cáncer ABC) were collected from January 2014 to January 2016 (2 year period).
As a requisite patients had to count with the computed tomography study (CT abdomen-pelvis protocol) in our hospital,
as well as the Dual-energy X-ray absorptiometry study (DXA); both studies were had to be divided by a time lapse of less than a month
Finally patients who did not count with...
Results
108 patients with a diagnosis of breast cancer were studied; the average age was 58.49±11.01 years,
with a range of 48 years (34 to 48 years).
In table 1 the frequencies of the risk factors related to lifestyle and comorbidities.
29.6% of the patients were overweight and 16.7% were obese,
the minimum BMI was 18 kg/m2 and the maximum was 39 kg/m2.
In respect to the gynaeco-obstetrical history,
the frequency of early menarche was 3.7% (4 cases),
none of the patients presented late menopause and...
Conclusion
In this research computed tomography was used to describe,
through Hounsfield Units,
the osseous profile of Mexican female patients with breast cancer.
Their osseous profile was related with the result obtained from the X-Ray Dual Absorptiometry study,
which is considered the golden standard for the diagnosis of mineral osseous density. The average age of our patients to the moment of the breast cancer diagnosis resulted similar to those reported by other Mexican authors like Sanchez,
Parada-Huerta,
Hernández,
and Bandala.
With respect to the familiar antecedent...
References
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Girish C,
Vijayalakshmi P,
Mentham R,
Rao CB.
A REVIEW ON BREAST CANCER.
Int J Pharm Bio Sc.
2014;4(2):47–54.
2.
Soto-Perez-de-Celis E,
Chavarri-Guerra Y.
National and regional breast cancer incidence and mortality trends in Mexico 2001–2011: Analysis of a population-based database.
Cancer Epidemiology.
Elsevier Ltd; 2016 Apr 1;41:24–33.
3.
Archivo clínico Centro Médico ABC.
4.
Youlden DR,
Cramb SM,
Dunn NAM,
Muller JM,
Pyke CM,
Baade PD.
The descriptive epidemiology of female breast cancer: An international comparison of screening,
incidence,
survival and mortality.
Cancer...