Coronary Artery Disease (CAD) is a multifactorial disease and its prevalence and incidence have been difficult to assess, depending on the definition that has been used1. In fact, while in the past it was used to consider CAD as a disease due to narrowings of ≥50% in the left main coronary artery or in the proximal tract of LAD and ≥70% in one or several of the major coronary arteries, nowadays understending and considerations about CAD are considerably different. So, up to now, some authors...

We retrospectively analyzed 72 patients with known CAD (43 males and 29 female, mean age 66±13; cardiac risk factors analysis in fig. 1) identified in a previous CT analysis (plaques analysis in fig. 2), who underwent stress CMR (3.0-T) in our center (San Salvatore Hospital, University of L’Aquila). In all studies, MOLLI sequences were acquired before and during adenosine infusion, and at the end of exam in order to calculate ECV value; all CMR sequences were analyzed with a dedicated software (Cvi42, Circle). In this...

A total of 72 patients with known CAD was analyzed. We divided our patients in two groups, based on perfusion and LGE images positivity: 1. infartuated/ischemic patients and 2. Non ischemic patients. 1. Infartuated/Ischaemic Patients. 38 patients showed infuartuated (with myocardial scar suggestive for underlying myocardial infarction ) or ischemic (reversible perfusion defect during adenosin infusion) myocardium. As expected, this patient showed high values of T1 mapping at rest (1412,48±58ms in infartuated patients and 1,300.12±68.36ms in ischaemic patients) and no significative reactivity during adenosine infusion...

We retrospectively analized 72 patients affected by CAD, diagnosed by a previous CardiacCT exam, who underwent Cardiac MR in order to study coronary flow reserve. According CT exams, about the 42% of study population showed a hemodinamically significative plaque. During the first qualitative evaluation of CMR exams, we identified potential perfusion defects, at rest or only during stress with adenosine infusion (reversible defects), or the presence of myocardial scar, suggestive for underlying myocardial infarction. Thank’s to this first evaluation, we differentiated our study population in...

[1] 2013 ESC guidelines on the management of stable coronary artery disease. The Task Force on the management of stable coronary artery disease of the European Society of Cardiology. European Heart Journal (2013) 34, 2949–3003 doi:10.1093/eurheartj/eht296 [2] Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030.PLoS Med.2006 Nov;3:e442 [3] Role of Adenosine in Pathogenesis of Anginal Pain. Filippo Crea, MD et al. (Circulation 1990;81:164-172) [4] Lipton MJ, Bogaert J, Boxt LM. Imaging of ischemic heart disease. Eur Radiology....