Aims and objectives
Recently,
as the accessibility to radiologic examination such as computed tomography (CT),
magnetic resonance imaging (MRI),
and ultrasonography (US) has expanded,
the detection rates of asymptomatic cystic lesions of the pancreas has increased.
Serous cystic neoplasms (SCNs) comprise 10–16% of all cases of pancreatic cystic lesions [1-3]; unlike mucinous lesions such as intraductal papillary mucinous neoplasm (IPMN) or mucinous cystic neoplasm (MCN),
almost all SCNs do not progress to malignancy.
[4] In addition,
in a recent large multicenter study,
the disease-specific mortality rate of serous...
Methods and materials
Patients: In this retrospective study,
33 patients (8 male,
25 female; age 26–74 years; mean age,
55 years) including one patient with two SCNs were selected for the analysis of the 34 lesions from our institution for an 11-year period (January 2006 – December 2016).
Besides the demographic information that included the presenting symptoms and past medical histories,
the surgical indication for each patient was also obtained from the electronic medical records (Table 1).
Imaging Data: All 33 EUS procedures in this study were performed...
Results
Surgical indication: The most common indication for surgery was uncertainty or misdiagnosis of other lesions (IPMN,
n=15; MCN,
n=2; solid pseudopapillary tumor,
n=3; neuroendocrine tumor,
n=3; cancer,
n=2) with a malignant potential or demonstrating malignancy (n=25,
74%),
followed by large lesion size (5.1–10 cm in the longest dimension; n=4,
12%) and the presence of relevant symptoms associated with the lesion (abdominal pain; n=2,
6%).
Among these 25 lesions,
SCN was suggested for 13 lesions on CT&MR,
but EUS suspected other differential diagnosis (IPMN,
n=7; solid...
Conclusion
The aim of this study was to assess the EUS features of pancreatic SCNs in determining surgical removal compared to the CT or MRI features.
In the present study,
the majority of the surgically confirmed SCNs showed a gross morphology of a mixed appearance comprising both microcystic and macrocystic components.
In such cases,
many of the lesions were diagnosed as branch duct type IPMN with a high risk of malignancy on EUS even in cases suspected to be SCN on MRI according to the microcystic...
Personal information
H.
Hwang,
MD,
Department of Radiology,
Gangnam Severance Hospital,
Yonsei University College of Medicine,
211 Eonju-Ro,
Gangnam-Gu,
Seoul 06273,
Korea
Tel.
+82-2-2019-3510
Fax.
+82-2-3462-5472
E-mail:
[email protected]
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