Aims and objectives
Cancer commonly metastasizes to bone and up to 80% of breast,
prostate,
and lung cancer patients will have bone metastases.
The site and distribution of bone metastases,
and the presence of skeletal complications such as pathologic fracture and spinal cord compression affect the patient's prognosis.
The treatment purpose is to palliate pain and prevent complications by reducing the length of hospital stay and by improving performance status.
Standard treatments include systemic therapies,
such as hormonal therapy,
analgesics and bisphosphonates,
and local,
focused on the lesion,...
Methods and materials
Series selection
Our series was collected between March 2015 and July 2016.
We performed 19 procedures (9 men and 10 women) in patients with skeletal metastases (Hip,
femur,
tibia and spine) from breast (12),
lung (4),
colon (2) and prostate (1) cancer.
All procedure was performed with multislice CT-guide with or without fluoroscopy.
Lesion diameter ranged from 2,0 – 9,0 cm.
Patients mean age 68 y; range 53-78 y.
In our series,
all treated lesions were osteolytic.
Patient selection
Patient selection was performed by a...
Results
All procedures were successfully completed.
Mean overall procedure time was 48 ±12 min.
On the day of the procedure,
the mean VAS score was 6,5 ± 1,5 (range 4,5–8,5).
It decreased to 1,9 ±1.3 by the 24-hour postoperative time point and was 1,5 ± 1.2 at 1 week and 1,34 ± 1.8 at 1 month.
The mean VAS score at all of the post-operative time points differed significantly from the preoperative baseline score (P: 0.05).
2 patients (11 %) were symptomatic at 1 month,
although...
Conclusion
The purpose of this study was to evaluate the results and complications of combined percutaneous biopsy,
microwave thermoablation and cementoplasty,
performed at the same time using a CT-guided approach,
to obtain pain resolution.
Our personal experience confirms that combined technique,
with CT-guided approach,
is an optimal first-line procedure for treating pain in patients with symptomatic bone metastases not sufficiently responsive to medical therapy.
The use of the CT-guide increases accuracy and safety in the various phases of the procedure,
reducing the risk of complications.
Personal information
Dr.
Vincenzo Costanzo,
Dipartimento di Scienze Radiologiche,
Di.Bi.Med.,
Università di Palermo,
Via del Vespro 127,
90100,
Palermo,
Italia; Phone: +393498189666; Mail:
[email protected]
References
1.
Linee guida trattamento delle metastasi ossee; AIOM; Edizione 2016.
2.
Janjan N.
Bone metastases: approaches to management.
Semin Oncol.
2001;28:28–34.
3.
Massie MJ,
Holland JC.
The cancer patient with pain: psychiatric complications and their management.
J PainSymptom Manag.
1992;7:99–109.
4.
Daniel Yaffe,
Ghal Greenberg,
Joseph Leitner,
Reuven Gipstein,
Myra Shapiro,
and Gil N.
Bachar ; CT-Guided Percutaneous Biopsy of Thoracic and Lumbar Spine: A New Coaxial Technique; AJNR Am J Neuroradiol 24:2111– 2113,
November/December 2003.
5.
WCG Peh,
FRCP,
FRCR CT-guided percutaneous biopsy of...