Aims and objectives
Growth is one of the most important characteristics of lung cancer[1-3].
Research data show that when low-dosecomputed tomography(CT) scan is used for baseline screening of lung cancer,
the detection rate of pulmonary nodules is 5%-51% in the general population with 20% on average per round.
Most (> 90%) nodules are benign[4-6].
Many suspected nodules are stable during 1-2 years of follow-up visits,
and thus excluded from the positive ones[5,7].
If the nodules during follow-up visits are...
Methods and materials
This study was approved by the institutional review boards (First Affiliated Hospital of Hainan Medical College) with a waiver of informed consent. Benign pulmonary nodules were found in 5 cases,
including 2 males and 3 females with an age range of 43-63 years old and a lesion size of 3.6-30.57 mm at the initial examination.
CT examinations were performed at slice thickness of 1-8 mm for 3 times at least and 5 times at most.
Except that 1 case of sclerosing hemangioma only had the data of 3mm...
The doubling time and imaging features of the benign nodules in 5 cases were shown in Table 1 and Figures 1-12.
Benign nodules can grow slowly[9,11].
Except one case had sclerosing hemangioma grown slowly (with a doubling time of 1697 days),
3 cases had solid nodules,
1 case had pure ground-glass opacity nodule with a doubling time same as that of lung cancer.
Literatures have recorded that the doubling time of lung cancer is generally <400 days [mean: 149 days and range: 20-400 days.
Only upon the doubling time,
the growing nodules in 4 cases are likely to be misdiagnosed as lung cancers....
Department of Radiology,
First Affiliated Hospital of Hainan Medical College,
31 Longhua Road ， Haikou,
Hainan ， China email@example.com Qun Li，M.D.
Ph.D. Department of Pathology,
Hainan Medical College,
33 Longhua Road，Haikou,
1. Xu DM,
van der Zaag-Loonen HJ,
et al（2009） Smooth or attached solid indeterminate nodules detected at baseline CT screening in the NELSON study: cancer risk during 1 year of follow-up.
Radiology 250(1):264-272. 2. MacMahon H,
et al（2005）Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society.
Radiology 237(2):395-400. 3. Revel MP,...