Using a 5-point Deauville scale suggests a visual or semi-quantitative comparison of 18F-fluorodeoxyglucose (18F-FDG) accumulation in metabolically active pathological foci with reference tissues - the surrounding background, mediastinal blood pool or liver. In the semi-quantitative analysis 18F-FDG standardized uptake value (SUV) is calculated [1]. Our aim was to analyze interpretation of whole body positron emission tomography with 18F-FDG combined with X-ray computed tomography (PET/CT) in patients with lymphoma after completion of chemotherapy (ChT), to assess reproducibility of established categories and prognostic properties of Deauville scale,...

This is a retrospective study of 89 patients with lymphoma who underwent whole body (WB)PET/CT after completion of ChT during 2015-2017 in Republican Center of Positron Emission Tomography. Hodgkin lymphoma (HL) occurred in 34 people, non-Hodgkin lymphoma (NHL) in 55. All patients were observed for at least 6 months after PET/CT. The interval from the completion of ChT until the PET/CT was 41±29 days. Preparation of the patient included fasting for at least 6 h and restriction of physical activity during the day before the...

Stages of lymphoma were distributed as follows: stage I - 5 patients, II - 28, III - 21, IV - 35. The number of ChT courses was from 3 to 8.Additional treatment after PET/CT was performed in 46 (52%) patients, including 20 with LH and 26 with NHL. Examples of the establishment of Deauville categories 1-5 are shown in Figure 1. First of all, in the analysis of PET/CT images, the foci of physiological and non-tumor 18F-FDG accumulation were excluded. The exact differentiation was difficult...

1. The high reproducibility of the Deauville categories established by different physicians was proved in 18F-FDG PET/CT studies performed in patients with lymphoma after ChT, which is consistent with data from other studies [6]. 2. The non-specific 18F-FDG accumulation in organs and tissues (sarcoidosis, inflammatory foci in the lungs, reactive lymph nodes) can lead to false positive PET findings. Diffuse 18F-FDG accumulation in the bone marrow may be a result of its activation after ChT and shouldn't be regarded as a lesion [2]. 3. PFS...

1. Boellaard R., Delgado-Bolton R., Oyen W.J., et al. FDG PET/CT: EANM procedure guidelines for tumour imaging: version 2.0 // Eur. J. Nucl. Med. Mol. Imaging. – 2015. – Vol. 42, N 2. – P. 328-354. 2. Cheson B.D., Fisher R.I., Barrington S.F., et al. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification // J. Clin. Oncol. – 2014. – Vol. 32, N 27. – P. 3059-68. 3. Barrington S.F., Mikhaeel N.G., Kostakoglu L., et al. Role...