Evaluation of a point shear wave elastography technique for assessment of liver fibrosis using transient elastography as reference method: preliminary results

Congress:

ECR 2018

Poster Number:

C-2469

Type:

Scientific Exhibit

Keywords:

Liver, Abdomen, Spleen, Elastography, Education, Cirrhosis

Authors:

I. Sporea, R. Sirli, R. Lupusoru, S. Nistorescu, C. Foncea, R. Mare, M. Danila, A. Popescu; Timisoara/RO

DOI:

10.1594/ecr2018/C-2469

DOI-Link:

https://dx.doi.org/10.1594/ecr2018/C-2469

Fig. 2: Regression analysis of stiffness values measured with Samsung when compared...

Fig. 1: Samsung Medison RS80A Ultrasound Machine

Fig. 3: ROC curve for F≥2

Fig. 4: ROC curve for F4

Aims and objectives

To compare the feasibility and the liver stiffness values obtained by means of a pSWE technique vs. Transient Elastography.

Methods and materials

Liver fibrosis is an important prognostic factor in chronic liver disease. It's severity can be assessed invasively (by liver biopsy) or non invasively (by elastography or by biologic tests). According to EFSUMB guidelines [1] ultrasound based elastographic methods are divided into: Strain Elastography Shear Waves Elastography(SWE): -Transient Elastography -Point Shear Waves Elastography using ARFI technology (Virtual Touch Quantification- VTQ, ElastPQ and Samsung) -2D-Shear Waves Elastography (SSI, GE, Toshiba) Our study included 89 subjects with or without chronic liver disease, in which liver stiffness (LS), as...

Results

All 89 patients had 10 valid measurements obtained by pSWE, but after applying the quality criteria, reliable LS measurements were obtained in 76/89 cases (85.3%). Reliable LS measurements by means of TE were obtained in 89/89 cases (100%). 76 patients were included in the final analysis. The mean LS values by pSWE and TE were very similar: F0-1: 5.6±1.39 kPa vs. 5.29±1 kPa, p=0.2; F2-3: 8.64±1.3 kPa vs. 7.9±2.6 kPa, p=0.2,but for F4 the mean values obtained by pSWE were significantly lower as compared to...

Conclusion

pSWE is a feasible method for assessing liver fibrosis. pSWE results strongly correlate with TE results.

Personal information

References

[1]EFSUMB Guidelines and Recommendations on the Clinical Use of Ultrasound Elastography. Part 1: Basic Principles and Technology:J. Bamber, D. Cosgrove, C. F. Dietrich, J. Fromageau, J. Bojunga, F. Calliada, V. Cantisani,, J.-M. Correas, M. D’Onofrio, E. Drakonaki, M. Fink, M. Friedrich-Rust ,O. H. Gilja, R. F. Havre, C. Jenssen, A. S. Klauser, R. Ohlinger,,A. Saftoiu, F. Schaefer,I. Sporea, F. Piscaglia.Ultraschall Med. 2013 Apr;34(2):169-84. [2] Tsochatis EA, Gurusamy KS, Ntaoula S, Cholongitas E, Davidson BR, Burroughs AK. Elastography for the diagnosis of severity of fibrosis in...