Aims and objectives
Obesity is a chronic and multifactorial disease resulting from an interaction between social,
behavioral,
cultural and genetic factors.Nowadays,
obesity is considered a serious public health problem,
presenting an increasing prevalence in recent decades in several populations (1).
Obesity,
generally,
results from an imbalance between ingested and consumed energy.
In a normal individual,
adipose tissue represents about 20% of body weight,
being the largest organ of the human body and it is located mainly at the subcutaneous and visceral level.
Its distribution is determined genetically and...
Methods and materials
214 individuals (aged between 18-25 years),
were submitted to a DEXA exam for the determination of %BF and android fat (AF) for all body,
classified in four groups using the Bray criteria (2003); and submitted to blood sampling for biochemical analyses: glycemia,
triglycerides,
total cholesterol and HDL,
and insulin resistance.
Data was analysed by SPSS vs23 software.
Correlation was assessed by the Pearson coefficient.
Fat parameters and biochemical analysis were compared by Student's t-test.
The association between anthropometric variables and cardiovascular risk factors was analysed...
Results
The prevalence of obesity was 9.09% in male genderand 16.6% in female gender,
with the average of the ABDF,
respectively,
is 17.49% and 29.27% (p=0.000).
There was a positive correlation of insulin resistance with BF (p=0.023),
with total cholesterol (p=0.001) and triglycerides (p=0.019) only in females.
Also in females,
a positive correlation was observed between total fat and triglycerides (p = 0.030).
With the multivariate linear regression,
we verified that both predictive models of BF and AF expressed a modest explanatory model (R2≈0.4) associated to...
Conclusion
According with the results of this study,
Reaven (1967) and Golay (1987) demonstrated that in non-diabetic subjects,
the insulin resistance is associated to the development of hypertriglyceridemiaand the decrease of HDL (7,8).In fact all these changes are determinants for cardiovascular disease(9).In 1956,
Vague already defendedthe existence of distinct patterns of body adiposity distribution; associated with the android fat,
metabolic disorders and changes in glycemic metabolism (10).
Currently,
the association of abdominal obesity with the components of the metabolic syndrome is well established.
Patients with a...
References
1- Cinti S.
The Adipose Organ.
Nutrition and Health: Adipose Tissue and Adipokines in Health and Disease.
1999; 3-19
2- Nicklas BJ,
Penninx BW,
Cesari M,
Kritchevsky SB,
Newman AB,
Kanaya AB et al.
Association of visceral adipose tissue with incident myocardial infarction in older men and women: The Health,
Aging and Body Composition Study.
Am J Epidemiol 2004,
160(8):741-9)
3- Lemieux I,
Poirier P,
Bergeron J,
Alméras N,
Lamarche B,
Cantin B et al.
Hypertriglyceridemic waist: A useful screening phenotype in preventive cardiology? Can...