Aims and objectives
Transrectal ultrasound-guided prostate biopsy favored in the early diagnosis of prostate cancer [1-3].
Different complications occur after prostate transrectal ultrasound-guided biopsy including infectious complications,
such as pyuria,
bacteriuria,
and fever; hemorrhagic complications including hematuria; relatively minor complications such as vasovagal syncope due to the pain of biopsy; and significant complications,
such as structural damage to surrounding anatomical structures and infectious septicemia,
can occur [4,5].
Prospectively studied complication rates on the basis of the difference in the number of biopsy cores (6-,
8-,
and 12-core methods)...
Methods and materials
The retrospective study of 347 patients underwent prostate transrectal ultrasound-guided biopsy done by radiologist passed fellowship in the same area.
Each patient received prophylactic antibiotics of 200-mg ciprofloxacin 1 hour before biopsy and later every 12 hours for five days after the biopsy.
The pre-biopsy enema done with saline solution 1 hour before the procedure in scheduledpatients.An automated biopsy gun loaded in a spring-action automatic biopsy device was used with disposable 18-gauge needles following either the 6-core or more core biopsy method with a transrectal...
Results
After the biopsy,
the specimens sent for pathological analyses where the following results were detected: adenocarcinoma - 187,
atypical gland suspected of adenocarcinoma - 22,
adenomyomatosis hyperplasia - 45,
atypical adenomyomatosis hyperplasia - 47,
atrophy and inflammation - 30,
high grade prostatic intraepithelial neoplasia - 16 (Table 2).
There were noted 21 cases (6.1%) from the 347 patients having experienced complications,
including:urinary retention -7 cases or 33%,
prostatitis – 6 (29%),
vasovagal syncope -4 (19%),
temperature – 2 (9%),
hematospermia – 1 (5%),
and hematuria...
Conclusion
The transrectal ultrasound-guided biopsy is a safe and effective diagnostic tool in the detection of cancer and other pathology of the prostate.
Sufficient training and experience of radiologists,
notes of the vessels prostate distribution clarifying the target in the prostate and avoiding vessels damages,
using the whole spectrum of ultrasound grayscale criteria’s,
patient’s prophylactic antibiotics and pre-biopsy enema can be useful for preventing severe complications due to transrectal ultrasound guided prostate biopsy.
Personal information
Prof.AndriasM.
Hambardzumyan
St.
Astvatsamayr Medical Center,
Department of Radiology
Address: Artashisian str.
46a,
0039 Yerevan,
Armenia
Endovision Medical Center
E-mail:
[email protected]
References
1.
Rudzinski JK,
Kawakami J.,
(2014).
Incidence of infectious complications following transrectal ultrasound-guided prostate biopsy in Calgary,
Alberta,
Canada: A retrospective population-based analysis.Can Urol Assoc J2014;8(5-6): e301-5.http://dx.doi.org/10.5489/cuaj.1751.
2.
Chan ES,
Lo KL,
Ng CF,
Hou SM,
Yip SK.
(2012).
A randomized controlled trial of antibiotic prophylaxis regimens for transrectal ultrasound-guided prostate biopsy.
Chin Med J (Engl),
125:2432-5.
3.
Yip SKh,
Sim HG.
(2010) Robotic radical prostatectomy in East Asia: development,
surgical results,
and challenges.Curr Opin Urol,
20:80-5.
4.
Rietbergen JB,
Kruger AE,
Kranse R,
Schroder...