Use of 18F-FDG PET CT in cutaneous malignant melanoma

Congress:

ECR 2019

Poster Number:

C-1821

Type:

Educational Exhibit

Keywords:

Oncology, Hybrid Imaging, Nuclear medicine, PET-CT, PET, Molecular imaging, Education, Staging, Cancer, Metastases, Neoplasia

Authors:

X. S. Herdoíza Salinas¹, P. A. CUASPUD ², J. Nieto², A. A. Roca¹, C. villareal², J. A. RUIZ LÓPEZ ³, P. Cornejo², A. Martínez², A. G. SEGURA²; ¹Quito, Pichincha/EC, ²QUITO/EC, ³403, qu/EC

DOI:

10.26044/ecr2019/C-1821

DOI-Link:

https://dx.doi.org/10.26044/ecr2019/C-1821

Fig. 1: Primary melanoma can disseminate to satellite mets (<2cm of distance from...

Fig. 10: Cutaneous melanoma TNM 8 Parameters. Brierley J, Gospodarowicz MK (Mary K.,...

Fig. 11: Cutaneous melanoma Staging TNM8. Brierley J, Gospodarowicz MK (Mary K.,...

Fig. 2: Cutaneous melanoma in face: look parotid nodes, postauricular nodes, nodes at...

Learning objectives

Review the TNM 8 classification of melanoma. Review the indications of 18F FDG PET CT in cutaneous malignant melanoma. Learn about the 18F FDG PET CT protocol in cutaneous malignant melanoma and what parameters allow to suspect metastasis.

Background

What is PET CT? Positron emission tomography-computed tomographyis anuclear medicinetechnique which combines apositron emission tomography(PET) scanner and a tomography(CT) scanner, to acquire images that demonstrate the metabolism of a tissue. The most used radiopharmaceutical is fludeoxyglucose F-18, allowing to assessthe tissue uptake of glucose. What is cutaneous melanoma? Cutaneous malignant melanoma is the result of uncontrolled proliferation and/or malignant transformation of the melanocytes located in the basal epidermal layer of human skin(1). Other locations where melanocytes can be found: eyes, ears, gastrointestinal tract, leptomeninges, oral...

Findings and procedure details

Rol of 18F-FDG PET CT in Cutaneous Melanoma: The PET-CT 18F-FDG study in melanoma is the most sensitive for the search for distant metastasis(12). It is applied in early stages with sentinel node invasion and stages III and IV according to the TNM classification 8(11). Fig 12-14. Their contribution to the management of the patient is related to the assessment of the response to treatment, re-staging and/or monitoring of the disease. The 18F-FDG PET-CT is more sensitive than other tracers in the detection of distant...

Conclusion

The 18F-FDG PET-CT is the study of choice for the detection of distant metastasis in cutaneous malignant melanoma, influencing the therapeutic and prognosis of the patient.

Personal information

X. S. HERDOÍZA SALINAS U.S.F.Q. /Carlos Andrade Marín Hospital / Quito. Ecuador. email: [email protected]

References

Dinnes J, Saleh D, Newton-Bishop J, Cheung ST, Nathan P, Matin RN, et al. Tests to assist in the staging of cutaneous melanoma: a generic protocol. Cochrane Database Syst Rev [Internet]. 2017 Sep 25;(9). Available from: http://doi.wiley.com/10.1002/14651858.CD012806 Patricio C, Limas C, Cwilich RG, Del Ángel M, Jurado G, Villalobos Prieto A, et al. Anales Médicos Actualidades para el tratamiento del melanoma metastásico, estado del arte [Internet]. Vol. 62, Trabajo de revisión. Available from: www.medigraphic.org.mxwww.medigraphic.org.mx Ward WH, Lamberton F, Goel N, Yu JQ, Farma JM. Clinical...