To present and illustrate the thymic CT morphology in relation to age. To list and discuss the CT features in thymic pathology. To review the classification of thymic epithelial tumors. To discuss the differential diagnosis of anterior mediastinal masses.
histology and anatomy The thymus is a central lymphoid organ that plays an important role in the maturation of the immune system,
especially regarding the cellular immunity during childhood . The thymus arises in the sixth gestational week from the third and fourth branchial pouches and undergoes a descensus process towards its final location,
in the anterior mediastinum,
behind the sternum and anterior to the pericardium and great vessels,
and may extend...
Findings and procedure details
A retrospective study of 15 years including 180 patients,
aged 1- 80 years who have undergone a thoracic CT exam,
performed without and with contrast injection,
followed by MPR reconstructions in coronal and sagittal plane,
for suspicion of anterior mediastinal masses or in the context of myasthenia gravis / myasteniform syndrome . In the current study,
60 patients had normal thymic features ,
whilst 120 patients presented with anterior mediastinal masses . The dominant pathologies were...
In the context of continuously changing thymic morphology,
it is important to be familiar with its normal CT aspects.
Its shape is quadrilateral/ triangular with convex lateral borders before puberty and triangular with straight or concave lateral borders after puberty.
The size and density of the gland decrease with age. The main differential diagnosis of masses involving the anterior mediastinum may be summarized by the mnemonic “4T”: thymoma,
thyroid tumors/ goiter and terrible...
Dr.Adriana Selea mail:email@example.com Prof.Dr.Ioana G.Lupescu mail:firstname.lastname@example.org Radiology,
Medical Imaging and Interventional Radiology,
Fundeni Clinical Institute,
UMPh Carol Davila,
. Smita Manchanda , Ashu S Bhalla , Manisha Jana ,
et al. Imaging of the pediatric thymus: Clinicoradiologic approach , World Journal of Clinical Pediatrics 2017,
6(1): 10-23; . Farbod Nasseri , Farzin Eftekhari, Clinical and Radiologic Review of the Normal and Abnormal Thymus: Pearls and Pitffals , RadioGraphics 2010,
30:413-428; . Mizuki Nishino,
Ashiku , Olivier N.
Kocher, et al. The Thymus: A comprehensive Review , RadioGraphics 2006,
26: 335-348; . Said Fadi Yassin ,...