To describe the newest us-guided non-thermal vein ablation technique with cyanoacrylate glue in treatment of chronic venous disease and to compare this procedure with traditional endovenous laser or radiofrequency ablation.

The prevalence of chronic venous disease (CVD)in the adult population has been reported to be as high as 60%, particularly affecting populations in the developed world [1,2]. It has become clear that CVD is an important cause of patient distress and significantly impacts on healthcare resources [3,4]. Although a complete understanding of the pathophysiology of CVD remains elusive, chronic venous hypertension is widely accepted as the predominant cause of advanced venous skin changes and ulceration. Symptoms of CVD:extremely variable and cause significant morbidity to patients,...

Cyanoacrylate is a device widely used in the medical field: Cardiac Surgery Vascular surgery Neurosurgery Otolaryngology surgery Thoracicsurgery General surgery Gynecological surgery There are several types of cyanoacrylate: Methyl 2-cyanoacrylate Ethyl-2-cyanoacrylate N-butyl cyanoacrylate 2-octyl cyanoacrylate The length of the side chains of the cyanoacrylate molecule determines the speed of polymerization : longer chains determine slower reaction speed. Polymerization is a CHEMICAL REACTION that leads to the formation of a chain polymer, that is a molecule made up of equal parts that repeat in sequence starting...

Cyanoacrylate is a new ultrasound-guided, minimally invasive ablative technique in treatment of CVD. Compared to the other treatments already widely used (laser / rfa) it has been shown to be simple, rapid, safe and effective. It is also characterized by better tolerability and less risk of peri- and post-operative complications. It can therefore be recommended as a valid treatment of chronic venous insufficiency.

1. Beebe-Dimmer JL, Pfeifer JR, Engle JS, Schottenfeld D. The epidemiology of chronic venous insufficiency and varicose veins. Ann Epidemiol 2005;15:175e84. 2. Robertson L, Evans C, Fowkes FG. Epidemiology of chronic venous disease. Phlebology 2008;23:103e11. 3. Van den Oever R, Hepp B, Debbaut B, Simon I. Socio-economic impact of chronic venous insufficiency. An underestimated public health problem. Int Angiol 1998;17:161e7. 4. Bradbury A, Evans C, Allan P, Lee A, Ruckley CV, Fowkes FG.What are the symptoms of varicose veins? Edinburgh vein study cross sectional population...