Aims and objectives
Most macroadenomas are soft allowing transsphenoidal resection.
However,
approximately 10% of Macroadenoma pituitary (PAM) are fibrous and may impact surgical approach and treatment outcome [1].
Numerous magnetic resonance imaging (MRI) based methods have been investigated in order to determine the consistency of pituitary macroadenomas (Ps).
Among these methods are the measurement of standard T1 and T2 signal and features of contrast enhancement,
diffusion and elastography (which are based on static imaging characteristics and cannot directly measure stiffness) [1-9].
These studies try to identify MRI findings...
Methods and materials
Patients and Methods
A total of forty-five patients who were diagnosed as macroadenomas (size > 1.0 cm) and admitted to our hospital between January 2010 and January 2018 were included in this study.
All patients underwent a transsphenoidal operation by a single surgeon,
who determined during the surgery the consistency of PAMs,
classifying them in accordance with its consistency in soft or fibrous.
Adenomas were classified of soft consistency if the tumor could be easily removed with curettage and aspiration.
On the contrary,
adenomas were...
Results
Table 01 presents clinical variables of patients.
Results for individual patients was presented in Table 02.
There were no differences in soft or fibrous tumors regarding,
age,
sex,
contrast enhancement patterns,
type of tumors and complete or incomplete surgical treatment. All 45 patients were first approached via transsphenoidal. From 45 patients,
25 (55%) were women and 20 (44%) were male.
Mean age of patients were 56 (SD=13.25) years,
ranging from 39 to 77 years. According to with surgical impression,
twenty-nine (47%) PAMs were classified as...
Conclusion
In this study,
we confirmed previous results of Smith et al [1],
showing that MRI ACP index can be used to predict pre-surgically PAMs consistency.
Our cut-off values were a little different being,
1.27 and 1.59.
In our series,
lower signal intensity on MRI T2-weighted was associated with fibrous tumors and correlated with neurosurgeon classification.
Concluding,
our study revealed the relationship between adenoma-to-cerebellar peduncle ratios and adenomas consistency. We showed that the adenoma- to-cerebellar peduncle ratio (ACP) is better than use the T2WI SI PAMs...
Personal information
Thaylla Maybe BedinotDa Conceiテァテ」o
e-mail:
[email protected]
[email protected]
Radiology Division.
Hospital de Clテュnicas de Porto Alegre,
Porto Alegre,
Rio Grande do Sul,
Brazil.
BRAIN - Basic Research and Advanced Investigations in Neurology 窶 Division of Neurology,
Hospital de Clテュnicas de Porto Alegre,
Porto Alegre,
Rio Grande do Sul,
Brazil.
PPGCM: Graduate Program in Medical Science.
Hospital de Clテュnicas de Porto Alegre,
Porto Alegre,
Rio Grande do Sul,
Brazil.
References
Smith KA,
Leever JD,
Chamoun RB.
Prediction of consistency of pituitary Adenomas by Magnetic Resonance Imaging.
J Neurol Surg B 2015; 76:340-343.
Hughes JD,
Fattahi N,
Van Gompel J,
et al.
Magnetic resonance elastography detects tumoral consistency in pituitary macroadenomas.
Pituitary 2016;19(3):286窶92.
Snow RB,
Johnson CE,
Morgello S,
et al.
Is magnetic resonance imaging useful in guiding the operative approach to large pituitary tumours? Neurosurgery 1990;26(5):801窶3.
Garcia-Navarro V,
Lancman G,
Guerrero-Maldonado A,
et al.
Use of a side-cutting aspiration device for resection of tumors during...