Aims and objectives
Human bocavirus (HBoV) is a newly identified pathogen that can cause upper and lower respiratory tract infections. In a recent prospective study,
HBoV was the fourth themost common pathogen in hospitalized children with respiratory tract diseases. However,
HBoV has been rarely detected in adults. Therefore,
the purpose of this study was to describe the clinical and radiologiccharacteristics of HBoV infections in adult using a large population cohort of a tertiaryhospital.
Methods and materials
Data collection This retrospective cohort study was conducted with the approval of the institutional review board at the Asan Medical Center,
and the requirement for informed consent was waived.
We searched the hospital database to identify all patients who had laboratory-confirmed HBoV infections between January 2010 and December 2017. Patient characteristics including demographics,
underlying chronic disease,
body mass index,
and features of HBoV infection,...
Patient characteristics and seasonality of HBoV infection Of the 185 patients with HBoV infections,
75 (40.5%) had upper respiratory infection alone and 110(64.3%) had pneumonia. Patient characteristics are shown in Table 1 . Coinfections were detected in 88 patients (47.6%).
The most frequent respiratory viral co-pathogens were rhinovirus (n=8,
10.7%) in URIand adenovirus (n=5,
4.6%) and influenza A or B virus (n=5,
4.6%) in pneumonia. Infections were predominantly noted between February and...
HBoV infection can cause respiratory infections in adults and is associated with a high incidence of pneumonia,
especially in nosocomial and older patients.Although neutropenia and lymphopenia were not significant risk factors for pneumonia in this study. The overall mortality rate of HBoV infection at 30 days(7.6%) was similar with those for other respiratory viral infections,
such as human metapneumovirus and RSV,
inadult patients (7-8%).Whereas HBoV infections in children showed a less...
Soo Hyun KIM,
Department of Radiology,Asan Medical Center,University of Ulsan College of Medicine,
Republic of Korea. Phone: +821085799389 e-mail : email@example.com
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