Aims and objectives
Analyze risk factors related to lung cancer in low-dose CT (LDCT) lung screening participants,
provide data support for identifying high-risk groups of lung cancer and improve the effectiveness of LDCT lung cancer screening.
Methods and materials
Subjects consisted of 5366 asymptomatic and voluntary participants (includes 2762 males and 2604 females) aged 40-87 years old,
who received LDCT in Cancer Hospital,
Chinese Academy of Medical Sciences between Jan 1 st ,
2014 and Dec 31 st ,
2017. Participants finished questionnaires relevant to risk factors and were provided Low-dose CT scans.
The LDCT Radiological results were interpreted according to the I-ELCAP Screening Protocol. Multivariate logistic regression examined associations of...
389 of the 5366 participants tested positive(including lung cancer) with LDCT,
26 cases pathologically confirmed lung cancers.
Age and smoking (previous
smoking and current smoking) are lung cancer and positive nodules ralated risk factors.
There was no risk factor for distinguishing between lung cancer and positive nodules(excluding lung cancer) groups. Stratified analysis of age did not identify any risk factor related to lung cancer and positive nodules compared with LDCT negative in 40-49...
smoking are risk factors related to lung cancer and positive nodules,
while ≥50 year olds with a history of smoking or tuberculosis may be a
high risk group for lung cancer in China.
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