Aims and objectives
Cardiovascular magnetic resonance (CMR) is a valuable tool for the evaluation of patients with,
or at risk for,
heart disease and has a growing impact on diagnosis,
clinical management,
and decision making [5-7].
The pattern of late gadolinium enhancement (LGE) helps to determine the underlying etiology of the heart failure [6].Determining the etiology of a cardiomyopathy is of clinical importance,
as it has implications with regards to the optimal treatment strategy and the prediction of prognosis.
The presence and extent of LGE may determine prognosis...
Methods and materials
Clinical and CMR data of 72 patients (46,9±15 yrs,
m/f=44/28) with a diagnosis of cardiomyopathy were analysed retrospectively.
Cases with known history of coronary artery disease and hypertrophic cardiomyopathies were excluded.
CMR images were obtained with 1.5T scanner.
Image analysis included assessment of heart chamber morphology,
volumes and function.
Patterns of LGE were analysed.
According to the pattern of heart chamber dilatation and clinical symptoms all the patients were divided into three groups (Fig. 1):
- syndrome of non-compacted myocardium (NCM,
n=30,
45,1±16,7yrs,
m/f=18/12);
-...
Results
Left ventricular non-compaction cardiomyopathy (NCM) is a rare structural abnormality of the left ventricular (LV) myocardium of uncertain etiology and with unknown molecular patho-mechanism.
LVNC is characterized by numerous prominent trabeculations and deep intertrabecular recesses in hypertrophied and hypokinetic segments of the left ventricle.The clinical presentation of the disease is highly variable,
ranging from asymptomatic one to severe heart failure and even sudden cardiac death[1].
In our study the patients with supposed diagnosis of NCM had a clinical signs ofarterial hypertension in 10% of cases,...
Conclusion
CMR helps to further clarify the exact type of non-ischemic cardiomyopathy in different groups of patients with heart chamber dilatation of unknown etiology.
In the case of suspected NCM CMR performs the role of a method that increases confidence of physicians in the accuracy of the diagnosis.
CMR allows to exclude structural abnormalities for patients with clinically suspected ARVC.
CMR improves the detection of structural myocardial changes in the group of patients with DCM.
References
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Boulaamayl,
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Raissouni,
M.,
Mouineet al.
(2017) ‘Left ventricular noncompaction-A rare form of cardiomyopathy: Revelation modes and predictors of mortality in adults through 23 cases.’,
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102–109.
doi: 10.1016/j.jsha.2016.02.004.
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Ellims,
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et al.
(2015) ‘Histological validation of cardiac magnetic resonance analysis of regional and diffuse interstitial myocardial fibrosis’,
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