Non-enhanced MRI DWIBS in assessment of liver metastasis in breast cancer patients

Congress:

ECR 2019

Poster Number:

C-1843

Type:

Scientific Exhibit

Keywords:

Hybrid Imaging, Liver, MR-Diffusion/Perfusion, PET-CT, Molecular imaging, Cancer

Authors:

M. M. A. Rezk¹, M. T. El-Diasty², A. Nazeer¹, Y. S. Habib¹, T. Raafat¹, M. Abu el dahab¹; ¹Cairo/EG, ²Jeddah/SA

DOI:

10.26044/ecr2019/C-1843

DOI-Link:

https://dx.doi.org/10.26044/ecr2019/C-1843

Fig. 1: DWIBS images show multiple metastatic lesions with restricted DWI signals

Fig. 2: T1/DWIBS fused images show multiple metastatic lesions with restricted DWI...

Fig. 3: DWIBS images show multiple metastatic lesions with restricted DWI signals

Fig. 4: summary between DWI and DWIBS

Aims and objectives

To assess the diagnostic performance of whole body diffusion weighted imaging with background suppression (WBDWIBS) and no contrast agents in assessment of liver metastasis in breast cancer patients compared to enhanced 18 FDG-PET-CT.

Methods and materials

50 patients with pathologically proven breast cancer having suspicious liver lesions by ultrasound; underwent both F-18-FDG PET-CT and WB-MRI/DWIBS. The study participants were categorized according to the phase of the disease at the time of presentation into two groups; pretherapy group including pathologically proved breast carcinoma lesions after biopsy or post-lumpectomy (A) , and post therapy group including patients who were receiving or had finished therapy (B). Ethical approval was granted by Institutional Review Board of the NCI before the study started. Informed consent was...

Results

F-18 FDG PET-CT demonstrated slightly higher specificity indices than MR-DWIBS while the MRDWIBS displays higher sensitivity indices than FDG PET CT. A high degree of the agreement also existed between DWIBS and PET CT.

Conclusion

WB-MRI/DWIBS is a promising tool in evaluation of liver metastasis in breast cancer patient. CLINICAL RELEVANCE/APPLICATION Easy technique for detection and assessment of metastasis with no radiation exposure or contrast agents.

Personal information

References

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