Aims and objectives
To report the frequency and discern potential reasons for liver magnetic resonance elastography technical failure in the clinical setting of a single institution.
Methods and materials
Eighty-nine magnetic resonance elastography (MRE) examinations performed from May 2017 to March 2018 in eighty-nine consecutive patients (mean age 53 years; male patients n=71 [80%]) were retrospectively analyzed. MRE examinations were performed on a 1.5T scanner (Signa HDx,
General Electric Medical Systems,
USA). Patients underwent MRE to diagnose or to stage liver fibrosis.
Table 1 shows the characteristics of study populations. Low amplitude mechanical waves at 60 Hz are...
MRE failed in 15 out of 89 exams (16.9%).
Reasons for failure were low T2* decay value in 13 patients,
subcostal liver in one patient and thick subcutaneous tissue layer in another patient. MRE technical failure was correlated with decreasing T2* value (OR 0,75 [0.65,
0.85] P<0.0001). A significant correlation between increasing BMI,
steatosis or a specific disease and MRE technical failure was not found. A T2* decay value ≤ 9.7 ms predicted MRE technical failure with a sensitivity of 100%...
MR Elastography (MRE) of the liver is a non-invasive technique that allows quantitative evaluation and staging of liver stiffness .
MRE is a safe,
and highly accurate technique that analyses a large area of liver parenchyma,
with good reproducibility.
It allows stiffness calculation even in the case of obese patients and in those with hepatic steatosis . One of the most frequent reasons for technical failure in MRE is hepatic iron overload as noted in previous works [1,
Ilaria Mussetto MD School of Radiology,
University of Genoa,
Department of Health Sciences DISSAL,
Via Antonio Pastore 1,
“Magnetic Resonanc e Elastography of Liver: Technique,
and Clinical Applications” Journal of Magnetic Resonance Imaging (2013) 37: 544–555 2. A.
Teytelboym et al.
“ Elastography in Chronic Liver Disease: Modalities,
and Future Directions ” Radiographics (2016) 36:1987–2006 3. J.
“Hepatic Fibrosis: Prospective Comparison of MR Elastography and US...