Purpose
Osteodensitometry is an internationally recognized method for the evaluation of the fracture risk in the diagnosis of osteoporosis. The radiological procedures like binary Roentgen absorptiometry (DXA) and the quantitative computer tomography (QCT) are equal to the quantitative ultrasound based methods (QUS). Concerning the security, with which therapies are pursued, experience and data position are much larger to the DXA than to QCT or QUS. The QUS procedures enable the measurement of three parameters: 1. Broadband ultrasound attenuation (BUA; dB/MHz) evaluate the cattering and absorption of...
Methods and Materials
55 female patients with first onset of Anorexia nervosa were included (age range from 10 up to 17 years). Exclusion criteria were any other chronic diseases or fractures with imobilisation of the legs. Bone density measurements at the Calcaneus were made at both sides five times with a SAHARA measuring instrument (Sahara, Hologic Inc., Waltham, the USA). The mean of the speed of sound (SOS; m/s) and the mean of the ultrasonic absorption (BUA; dB/MHz) were determined at both sides under comparable conditions in all...
Results
Baseline-measurementsAge-referred BUA smaller than -1 SD were found in 7/55 patients (12.7%). Normal values determined within 34/55 patients (61,8%), accelerated values were observed in 14/55 patients (25.5%). SOS was reduced over -1 SD within 10/55 patiens (18.2%), normally within 26/55 patients (47.3%), and accelerated within 19/55 patients (34.5%). Body-elevator-referring values were with < - 1 SD for BUA with 6 patients 10,9%), normally with 33 (60%) and accelerated within 16/55 patients (29.1%). SOS showed osteopenic values within 11/55 patients (20%), normal values within 22/55 patients...
Conclusion
Only few female patients within the study showed osteopenic bone density values with the sonographic evaluation compared with a regional normal population in the baseline evaluation. Sonographic entered values in the sense of an Osteoporosis were with no female patient. The accelerated SOS and BUA values contradict earlier study results, which reported predominantly reduced bone density values for female patients with Anorexia nervosa. A possible reason for our differing results is that in our study very young female patients were accepted and that the bone...
References
[1] Maugars YM et al. Eur J Endocrinol (1996) 135: 591-597.[2] Resch H et al. Calcif Tissue Int (2000) 66: 338-341.[3] Grinspoon S et al. Ann Intern Med (2000) 133: 790-794.[4]Wunsche K et al. Calcif Tissue Int (2000) 67: 349-355.
Personal Information
H.-J. Mentzel; Institutfr Diagnostische und Interventionelle Radiologie; Friedrich-Schiller-Universitt Jena; Bachstrasse 18; 07740 Jena; Germany; e-mail:
[email protected]. Korman; Klinik fr Kinder- und Jugendpsychiatrie,; Philosophenweg 3; 07740 Jena; Germany; e-mail:
[email protected]. Malich; Institutfr Diagnostische und Interventionelle Radiologie; Friedrich-Schiller-Universitt Jena; Bachstrasse 18; 07740 Jena; Germany; e-mail:
[email protected]. Wnsche; Institutfr Diagnostische und Interventionelle Radiologie; Friedrich-Schiller-Universitt Jena; Bachstrasse 18; 07740 Jena; Germany; e-mail:
[email protected]. Freesmeyer; Institutfr Diagnostische und Interventionelle Radiologie; Friedrich-Schiller-Universitt Jena; Bachstrasse 18; 07740 Jena; Germany; e-mail:
[email protected]. Vogt; Institutfr Diagnostische und Interventionelle Radiologie; Friedrich-Schiller-Universitt Jena; Bachstrasse 18; 07740...
