Purpose
To investigate the value of second look breast US with and without contrast enhanced MR volume navigation and fusion imaging (VNav) as reference.
Methods and Materials
Twenty-four patients (52±18 years, range 33-77) with additional lesions at conventional MR underwent bilateral contrast-enhanced (0.1 mmol/Kgbw Gd- BOPTA, Bracco Diagnostics) breast MR in supine position (1.5T, Achieva, Philips Healthcare) using T1-weighted high resolution isotropic examination volume and spectral attenuated inversion recovery fat suppression with body coil. Three fiducial, pills of vitamin E on the corresponding skin markers were used. US and MR coregistration was obtained by means of a magnetic transmitter positioned close to the patient and two small magnetic receivers positioned on a...
Results
Thirty-one additional lesions were detected in both MR exams. Pathologic examination showed 21 malignant and 10 benign lesions. Lesions diameter was 25±12 mm (mean±SD, range 7-43). 52% (11/21) of malignant and 60% (6/10) of benign lesions were detected only using VNav (p=0.0001). MR-guided biopsy was performed in three cases. Pathology demonstrated a 9 mm DCIS, a 8 mm sclerosing adenosis and a 12 mm atypical ductal hyperplasia.
Conclusion
Second look US with VNav showed a significant higher detection rate for additional MR-detected lesions increasing the possibility of tissue assessment using US- guided biopsy.
References
1. Sigurdson LJ, Kirkland SA. Breast volume determination in breast hypertrophy: an accurate method using two anthropomorphic measurements. Plast Reconstr Surg. 2006;118:313-320. 2. Kuhl CK, Schrading S, Leutner CC, et al. Mammography, breast ultrasound, and magnetic resonance imaging for surveillance of women at high familial risk for breast cancer. J Clin Oncol. 2005;23:8469-8476. 3. Sardanelli F, Podo F, D'Agnolo G, et al. Multicenter comparative multimodality surveillance of women at genetic-familial high risk for breast cancer (HIBCRIT study): interim results. Radiology. 2007;242:698-715. 4. Mann RM, Kuhl...
Personal Information
Alfonso Fausto, M.D.Consultant Radiologist, Diagnostic Imaging DepartmentSan Giovanni di Dio General HospitalViale Fatebenefratelli, 3434170 Gorizia - ItalyEmail:
[email protected] Ludovica Borghese, M.D. Consultant Radiologist, Diagnostic Imaging Department Casa di Cura Città di UdineViale Venezia, 410 33100 Udine, Italy Email:
[email protected] Giorgio Rizzatto, M.D.Director, Diagnostic Imaging DepartmentSan Giovanni di Dio General HospitalViale Fatebenefratelli, 3434170 Gorizia - ItalyEmail:
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