Purpose
INTRODUCTION:
Increased mammographic breast density is a moderate independent risk factor for breast cancer.
The odds ratio for developing cancer for the most compared with the least dense breast tissue categories ranges from 1.8 to 6.
Different classifications based on qualitative or quantitative criteria have been described.
One of the most common used is ACR (BIRADS) classification based on density categories.
[1]
Digital mammography (2DM) remains the most commonly used procedure for mammographic screening.
It performs bidimensional images while emitting the radiation dose in a...
Methods and materials
Patients selection
From September 2013 to September 2014 we began to use the synthesized-DM and the COMBO mode (2D-DM + DBT).
A total number of 8201 consecutive COMBO studies were performed at our institution in a clinical setting.
Synthesized reconstruction images were obtained from all DBT studies.
The informed consent was offered to all patients.
All the studies were performed using a Selenia Dimensions unit (Hologic,
USA).
Study design
We retrospectively selected an enriched sample with 136 patients (136 women,
medium age of 48.4 years...
Results
The distribution of the ACR density patterns for first readerwasthe following:
In both studies the percentage of patients with ACR a was the same.
In synthesized-DM there was a decrease of 4.7 % of patients with ACR b and 3.6 % of patients with ACR c.
However,
there was an increase of 8.3 % of patients with ACR d compared with 2D-DM.
The intra-observer kappa index for this first reader was 0.809 so substantial or almost perfect agreement was found which was statistically significant (p<0.001)....
Conclusion
1- Our results showed a trend to increase in ACR d density pattern when using synthesized-DM.
2- The intraobserver concordance was excellent for both readers.
3- The interobserver concordance was moderate for both techniques although slightly better for synthesized-DM.
References
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Ruiz-Perales F,
Miranda J,
Ascunce N,
González-Román I,
Sánchez-Contador C et all.
Evaluation of mammographic density patterns: reproducibility and concordance among scales.
BMC Cancer.
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2- Martínez Miravete P,
Etxano J.
Tomosíntesis de mama: una nueva herramienta en el diagnóstico del cáncer de mama.
Radiología.
2014.
http://dx.doi.org/10.1016/j.rx.2013.06.006.
3- Zuley ML,
Guo B,
Catullo VJ,
Chough DM,
Kelly AE,
Lu AH et all.
Comparison of two-dimensional synthesized mammograms versus original digital mammograms alone and in combination with tomosynthesis images.Radiology.2014;271:664-71.
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