Aims and objectives
Pancreatic adenocarcinoma is the most common neoplasm of pancreas,
representing 85% of pancreatic malignant tumors,
and it’s the fift most frequent malignancy in the adult.
Its prognosis is very poor,
with an estimated 5-years survival rate of 5%.
The prognosis is related to the fact that most of tumors (95%) are detected in an advanced stage.
The only potential curative tratment available for pancreatic cancer,
when not contraindicated for the advanced stage,
is surgical resection.
Following resection,
the 5-year survival rate of patients ranges from...
Methods and materials
Patient population
We reviewed the follow-up MDCTs of patients with resected adenocarcinoma of the pancreas performed between 2011 and 2017,
and selected 42 consecutive patients with detection of solid hypodense tissue in the resection area at CT and with further follow-up imaging available.
The study population included 22 males and 19 females with an average age at the time of the examination of 65,7 years.
CT imaging
MDTC examinations were performed using on a 64-row scanner (Philips Brilliance 64,
Philips Medical System,
Eindhoven,
Netherlands).
Patients...
Results
Results
Among the 42 patients,
follow-up MDTCs showed 19 patients with local recurrence and 22 patients with post-surgical scar tissue which remained stable for size and imaging features.
Average age at the time of examination was 66 for the local recurrence group and 65,4 for the scar tissue group.
Mean longest diameter of the post-surgery solid tissue in patients with tumor recurrence was 35.5±4.8 mm,
significantly larger than 21.4±1.6 mm measured in patients with stable fibrosis (p=0,0053).
RECURRENCE
FIBROSIS
p
MEAN LONGEST DIAMETER
35.5 (±4.8)...
Conclusion
In conclusion,
these preliminary results showed that tumor recurrence appears to be larger in size and with poorer progressive enhancement than post-surgical fibrosis.
Local recurrence appears to have no correlation with the presence of metastases,
pathological lymph-nodes and peritoneal carcinomatosis.
These results are going to be confirmed assessing a larger group of resected patients.
Personal information
A.
Mazzaro,
MD
Department Of Radiology,
Policlinico Universitario "G.B.
Rossi",
Borgo Roma,
Verona/IT
Piazzale L.A.
Scuro 10
37134 Verona (VR),
Italia
Phone: +390458124301
email:
[email protected]
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