Purpose
To evaluate the perceived diagnostic value of reconstructed synthetic two-dimensional (S2D) images when added to digital breast tomosynthesis (DBT).
Methods and materials
100 DBT examinations were reviewed in this reading study.
11showed proven breast malignancies.
Two independent breast radiologists (20 and 1.5 years of experience) assessed the cases after patient management was completed.
To simulate screening and diagnostic situations,
the readers were blinded on clinical history for 50 patients and un-blinded for the other 50 (6 malignant).
Readings were performed with DBT alone,
then with added S2D images.
Perceived added diagnostic value of S2D images was rated on 3-step scales: 0 to +2 for the group with...
Results
The addition of synthetic 2D images to DBT was scored beneficial overall in 40 cases (40%) and 53 cases (53%) by Reader 1 and Reader 2,
respectively.
Across all readers and subjects,
the addition of S2D views was perceived beneficial,
with no impact,
or negatively versus DBT alone in 41%,
55%,
and 4% of cases,
respectively (eaxmples in Fig.
1).
The addition of S2D images was rated particularly useful in the assessment of 79% of distortions and asymmetries (41 cases out of 52).
The Wilcoxon...
Conclusion
Synthetic 2D images may bring additional diagnostic value to DBT volumetric image sets alone,
in particular for assessing distortions and asymmetries.
References
SkaaneP,Bandos AI,Eben EB,Jebsen IN,Krager M,Haakenaasen U,Ekseth U,Izadi M,Hofvind S,Gullien R.
Two-viewdigitalbreasttomosynthesis screening with synthetically reconstructed projection images: comparison withdigitalbreasttomosynthesis with full-fielddigitalmammographic images. Radiology.2014Jun;271(3):655-63.
doi: 10.1148/radiol.13131391.
Van Schie G, Mann R, Imhof-Tas M, Karssemeijer N. Generating synthetic mammograms from reconstructed tomosynthesis volumes. IEEE Trans Med Imaging. 2013 Sep 16.
Wallis MG,
Moa E,
Zanca F,
Leifland K,
Danielsson M. Two-view and single-view tomosynthesis versus full-field digital mammography: high-resolution X-ray imaging observer study. Radiology. 2012 Mar;262(3):788-96.
doi: 10.1148/radiol.11103514
SkaaneP,Bandos AI,Gullien R,Eben EB,Ekseth U,Haakenaasen U,Izadi M,Jebsen IN,Jahr G,Krager...