Learning objectives
Liposarcomas can metastasize to different areas of the body but rarely metastasize to the liver.
Due to the unusual occurrence of metastases of liposarcoma to the liver,
the CT and MR imaging findings of 5 cases are going to be discussed in the light of literature.
Background
Liposarcomas are malignant tumor of mesenchymal origin.
Liposarcomas consists of five subtypes: well differentiated,
myxoid,
round cell,
pleomorphic,
and mixed.
The incidence of metastatic disease is 29–33% for myxoid,
13% for round cell,
and 40% for mixed (1).
Although liposarcomas are the most common soft tissue tumors of the limbs and retroperitoneum,
primary liposarcomas of omentum is rare.
The most common site of spread is to the lung from extremity sarcomas and the incidence is dependent on tumor grade and size.
The myxoid subtype is...
Findings and procedure details
CT IMAGING TECHNIQUE
CT examinations from the domes of the diaphragm to the symphysis pubis with 2.5 mm collimation,
2.5 mm intervals,
at 120kV were obtained on multidedector CT scanner (GE,
Medical Systems,
Milwaukee,
Wis,
USA).
All patients received 1250ml of diluted (3%) water with soluble contrast material orally,
periodically over 1.5hr before the scan and in addition to that,
250ml just before the study,
to opasify the stomach,
small bowel and colon.
Non-opasificed bowel loops may be a source of diagnostic error that can...
Conclusion
Liposarcoma is malign mesenchymal tumor,
which may arise in any region of the body.
Liposarcoma is the most common primary malign neoplasm of the retroperitoneum,
but mesentery and peritoneum are rare locations.
On pathology liposarcomas are classified as well-differentiated,
dedifferentiated,
myxoid,
pleomorphic,
and round cell/cellular myxoid subtypes (2).
Well-differentiated group subdivided into four types; lipomatous,
sclerotic,
inflammatory,
and dedifferentiated liposarcoma.
Prognosis of the liposarcomas varies on the basis of the histological subtype (3,
4).
Liposarcomas can metastasize to different areas of the body but have...
References
REFERENCES
1.Tateishi U,
Hasegawa T,
Beppu Y,
Satake M,
Moriyama N.
Primary Dedifferentiated Liposarcoma of the Retroperitoneum Prognostic Significance of Computed Tomography and Magnetic Resonance Imaging Features J Comput Assist Tomogr 2003;27:799-804.
2.
Enzinger FM,
Weiss SW.
Soft Tissue Tumors.
4th ed.
St Louis,
MO: Mosby- Year Book,
2001.
3.
Jelinek JS,
Kransdort MJ,
Shmookler BM,
Aboulafia AJ,
Malawer MM.
Liposarcoma of the extremities: MR and CT findings in the histologic subtypes.
Radiology 1993;186:455-459.
4.
Reitan JB,
Kaalhus 0,
Brennhovd 0,
Sager EM,
Stenwig AE,...