Aims and objectives
Renal cancer carcinoma (RCC) is the most common cancer of renal parenchyma (1,2).
The incidence of RCC has varied significantly over the last two decades worldwide (3,4).
There is a higher prevalence of clear cell RCC that has the worst prognosis of all subtypes (5,6).
Therefore,
the histological classification of RCCs is extremely important and the imaging features are largely studied considering the significant implications of the subtypes in the prognosis (7).
The aim of this study is to determine whether enhancement phases and imaging...
Methods and materials
Patient selection
A retrospective study of patients followed on Department of Urology,
University of Sao Paulo Medical School General Hospital.
From January 2011 to December 2017,
all patients with renal mass who underwent a partial nephrectomy with previous CT were included in this present cohort.
CT imaging
All examinations were performed using a multidetector CT MDCT with 64 or 128 channels (Brillance,
Philips Healthcare or Aquilion CXL,
Toshiba).
For all patients,
the abdominal scan included precontrast and postcontrast phases (corticomedullary,
nephrographic and excretory phases).
Imaging...
Results
In total,
1,100 patients were diagnosed with a renal mass,
being 153 included in this sample with a unique lesion.
Among these,
108 (70,6 %) were clear cell renal cell RCC,
30 (19,6 %) were papillary RCCs,
and 15 (9,8 %) were chromophobe RCCs.
The baseline characteristics for each of the groups are demonstrated in Table 1.
Objective evaluation
The mean attenuation measurements according to each group are listed in Table 2.
In corticomedullary phase,
enhancement of clear cell RCCs was significantly greater than that...
Conclusion
In this study,
the renal mass differentiation between clear cell RCCs from other RCC subtypes (papillary and chromophobe) was statistically significant in corticomedullary,
nephrographic and excretory phases,
same results demonstrated by Zhang et al (8) and Young et al (9).
As demonstrated by Zhang et al,
some qualitative findings were related to clear cell RCC,
such as necrotic and cystic changes,
and the presence of the washout pattern.
Despite some overlaps,
the multiphasic MDCT imaging features and the degree of enhancement aid in the differentiation...
Personal information
Mário Henrique Verussa
Department of Imaging,
INRAD.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
R.
Dr.
Ovídio Pires de Campos,
75 - Cerqueira César
CEP 05403-010 - São Paulo/SP,
Brazil
E-mail:
[email protected]
Fernando Morbeck A.
Coelho
Department of Imaging,
INRAD.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
R.
Dr.
Ovídio Pires de Campos,
75 - Cerqueira César
CEP 05403-010 - São Paulo/SP,
Brazil
[email protected]
References
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2 - Protzel C,
Maruschke M,
Hakenberg OW.
Epidemiology,
Aetiology,
and Pathogenesis of Renal Cell Carcinoma.
European Urology Supplements.
2012;11:52-59.
3 - Kim SH,
Kim CS,
Kim MJ,
Cho JY,
Cho SH.
Differentiation of Clear Cell Renal Cell Carcinoma From Other Subtypes and Fat-Poor Angiomyolipoma by Use of Quantitative Enhancement Measurement During Three-Phase MDCT.
AJR 2016 jan; 21-28.
4 - Srigley JR,
Delahunt B,...