Learning objectives
1.
To describe MRgFUS fundamental phisical aspect
2.
To identify selection criteria
3.
To describe different application and results of MRgFUS in the treatment of painful bone lesion
Background
MRgFUS has become a valid minimally-invasive technique in the ablation approach of numerous pathologies.
Indeed,
clinical results achieved in the last few years in the treatment of bone tumors,
symptomatic uterine fibroids or essential tremors,
have lead to pay more attention to this high efficacy technique.
Among its application,
treatment of bone tumors is one of the most interesting field of application,
considering the fascinating results described in literature.
Notably,
MRgFUS effectiveness in the treatment of Osteoid Osteoma and in bone mets pain palliation are...
Findings and procedure details
Phisical principle
US waves are longitudinal mechanical waves which propagate in the medium as alternating zone of compression and rarefaction; thus each wave propagate through the displacement of the single particle in the medium which then return to the equilibrium,
dissipating the wave energy.
US waves can achieve different diagnostic or therapeutic effect depending mainly on different intensity and frequency.
Intensity and frequecy.
Intensity represent the energy of a single wave and it could beexpressed as the power delivered per unit area (W/cm2).
Therefore,
the...
Conclusion
HIFU treatment offers a completely non invasive approach.
Moreover,
imaging guidance gives a new interventional point of view thanks both to temperature checking and lesion visualization.
MRgFUS allows therefore the opportunity to visualize the real-time efficacy of the treatment and all potential adverse reactions including damage to sensitive organs.
Certainly,
the desirability of this procedure is comparable only to its complexity,
and a careful evaluation of the lesion and the district to be treated is mandatory to ensure an efficacy and safety treatment,
as well...
References
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“Pulsed Cavitational Ultrasound : A Noninvasive Technology for Controlled Tissue Ablation ( Histotripsy ) in the Rabbit Kidney,”J.
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[3]A.
Napoliet al.,
“Primary pain palliation and local tumor...