|ECR 2019 / C-1963|
|The role of multiple detector computed tomography in differentiating the primary small bowel neoplasms|
Methods and materials
Patient population: In this retrospective study of patient data from January 2015 to May 2018 in University medical center and Cho Ray hospital at Ho Chi Minh city, Vietnam. The inclusion criteria were as follows: pathologically proven primary small bowel neoplasms and MDCT performed with intravenous contrast media before biopsy or surgery. Gastrointestinal stromal tumors (GISTs) were defined in this study as CD117-positive . The periampullary tumors and lipomas were excluded. Lipomas are benign and able to make a definitive diagnosis based on CT density of less than 10 Hounsfield units, regardless of other imaging features. This retrospective study was approved by the institutional review board of our institution, which waived the requirement for informed consent from the patients.
Data acquisition: The protocols varied, depending on the reason of examination. All studies were at least venous phase, delay time to obtain images of approximately 60-70 seconds after injection. The images were acquired from the diaphragm to the perineum. All patients received an IV injection of 80-100 mL of non-ionic iodinated contrast material containing 300 mg I/mL at a rate of 3–4 mL per second. We did not use any oral contrast material or water to achieve small bowel distention.
Data analysis: The MDCT images were independently reviewed by two radiologists with 8 and 15 years of clinical experience in abdominal CT interpretation. The radiologists were blinded to the pathological information. The MDCT features of small bowel tumors were analyzed including anatomical distribution, pattern of growth, enhancement, hyperplasia vascular on tumor surfaces, size and lymph node characteristics. Then, comparing each finding to pathology report to evaluate the specificites, sensitivites and positive predictive value (PPV).
Statistical analysis: All statistical analyses were performed with the STATA. The used statistical tests were χ2, Fisher, Kruskal-Wallis, Wilcoxon-rank-sum. A p value < 0.05 was considered statistically significant.
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