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ECR 2019 / C-3047
The utility of dual energy CT in diagnosis of amiodarone induced lung disease: a prospective cohort study
Congress: ECR 2019
Poster No.: C-3047
Type: Scientific Exhibit
Keywords: Thorax, Respiratory system, CT, Computer Applications-Detection, diagnosis, Technology assessment, Drugs / Reactions
Authors: N. R. Bogot, I. Hadas-Halpern, J. Cohen, A. Rokach, G. Izbicki, O. Benjaminov, N. Arish; Jerusalem/IL
DOI:10.26044/ecr2019/C-3047

Results

According to DECT, 47%, 30% and 23% of the exams showed low, intermediate and high AILD probability respectively with high ICC among radiologists (r = .983) . Based on the clinical assessments, 67%, 19% and 14% of patients had low intermediate and high AILD probability respectively, with moderate ICC (r = .798) among pulmonologists. ICC between DECT and clinical diagnoses was moderate (r = .608).

 

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Out of the 83 examined patients: 2 patients had severe breathing artifacts and were excluded;  22(27%) patients had no parenchymal lung abnormalities, 17(21%) had air space opacities, 36(44%)  had areas of atelectasis (including linear atelectasis) , 33(41%)  had ground glass opacities and 8(10%)  had lung nodules (4-25 mm in size). On the iodine sensitive images among the 17 patients with air space opacities  10, 2 and 5 patients had absent, possible and definite iodine deposits respectively; among the 36 patients with areas of atelectasis 17, 7 and 12 patients had absent, possible and definite iodine deposits respectively; among the 33 patients with ground glass opacities 18, 10 and 5 patients had absent, possible and definite iodine deposits respectively; among the 8 patients with lung nodules 7 and 1 patients had absent and definite iodine deposits respectively.

Absent, possible and definite iodine deposits were identified in the liver parenchyma of 42(52%), 23(28%), 16(20%) patients respectively.

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