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ECR 2019 / C-1117
Multiparametric MRI with dynamic contrast enhanced MRI and diffusion weighted imaging for the assessment of non-mass enhancing breast tumours
Congress: ECR 2019
Poster No.: C-1117
Type: Scientific Exhibit
Keywords: Breast, MR-Diffusion/Perfusion, MR, Staging, Cancer, Pathology
Authors: M. A. Marino1, D. B. Avendano2, D. Leithner3, B. Bernard-Davila4, T. H. Helbich5, E. A. Morris4, M. S. Jochelson6, P. A. T. Baltzer5, K. Pinker-Domenig5; 1Messina/IT, 2Monterrey, Nuevo leon/MX, 3Frankfurt a. Main/DE, 4New York/US, 5Vienna/AT, 6New York, NY/US

Methods and materials

In this IRB-approved study, a prospectively populated database was searched for patients with a breast mpMRI and a suspicious NME lesion (BI-RADS 4/5).  95 patients were identified. 29 were excluded due to suboptimal quality/non-visibility of the lesion on DWI. Two readers (r1, r2) independently assessed the NME on DCE-MRI and DWI.  For each lesion they assigned a score for DCE-MRI according to BI-RADS lexicon. A 2D ROI was manually drawn in the most hypointense/suspicious area of the NME and ADC values were measured. MpMRI with DWI was assessed using a previously published reading method that adapted ADC-thresholds to the assigned BI-RADS classification.Sensitivity (SE), specificity (SP), diagnostic accuracy (DA) and kappa agreement were calculated.

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