Initial assessing the role of Whole-Body Diffusion-Weighted Magnetic Resonance Imaging (WBDW- MRI) in comparison with PET/CT for detection of metastases. Diffusion MRI is a specific Magnetic Resonance Imaging (MRI) modality that produces in vivo images of biological tissues weighted with the local microstructural characteristics of water diffusion. Whole-Body Diffusion-Weighted Magnetic Resonance Imaging (WBDW- MRI) has the potential to help detect primary tumors and metastasis. Differentiating benign from malignant lesions, and determining the presence of disease recurrence. DW- MR imaging enables qualitative and quantitative assessment of...

We retrospectively evaluated the cases of 43 patients (19 women, 24 men; age range, 42–65 years), diagnosed primary cancer. All the patients executed whole-body diffusion weighted MRI on the Siemens Avanto 1,5T MRI, syngo TimCT, Gradient 45 mTm SR 200 T/m/sec, 16-channel body- array coils and the results were compared with PEP/CT whole-body scanning (Biograph true D w/true V 64 slice, Siemens) at the same time. DW sequence was performed in the Axial plane (4000/78; matrix, 192 x 192; field of view, 384 x 384...

43 cases were executed whole-body MRI and PET/CT: 40 of 43 patients had confirmed metastasis. 1 case: showed additional small vertebral body metastasis that were not seen on PET/CT. 2 case: whole-body MRI showed one additional node in liver (metastasis) that was not seen on PEP/CT. 3 case Whole-body MRI showed one intra-abdominal lymph node (benign lymph node) that was not seen on PEP/CT. 1 case PET/CT showed one pelvic peritoneal focal had increased metabolic activity, that was not seen on MRI. All the cases...

Whole-body diffusion weighted MR imaging can be used for detection of metastases with high sensitivity. It can replace PET / CT in screening for cancer metastases in the future.

1 A. L. Baert, Leuven, M. F. Reiser, München, H. Hricak, New York, M. Knauth, Göttingen-MD; Diff usion-WeighteDiff usion-Weighted MR Imaging- Applications in the Body; Medical radiology 2 Bachir Taouli and Dow-Mu Koh; Diffusion-weighted MR Imaging of the Liver; Radiology January 2010 254:47-66. 3 Yoshiharu Ohno, Hisanobu Koyama, Yumiko Onishi, Daisuke Takenaka, Munenobu Nogami, Takeshi Yoshikawa, Sumiaki Matsumoto, Yoshikazu Kotani, and Kazuro Sugimura-MD ;Non–Small Cell Lung Cancer: Whole-Body MR Examination for M-Stage Assessment—Utility for Whole-Body Diffusion-weighted Imaging Compared with Integrated FDG PET/CT; Radiology August 2008...