Aims and objectives
To describe the different radiological characteristics of Soft Tissue Solitary Fibrous Tumour (SFT),
as well as correlation with clinical and pathological data.
Methods and materials
Retrospective analysis of the clinical history,
pathological exams and imaging tests of all cases diagnosed of soft tissue SFT in a tertiary hospital,
between 1995 and 2016.
A total of 36 cases were registered in a database performed by the pathological anatomy department of our hospital.
Of those,
27 cases had imaging tests available in our radiology department’s PACS,
including ultrasound,
computed tomography (CT),
magnetic resonance (MRI) and positron emission tomography (PET).
In each case,
the following data was collected:
Age
Gender
Clinical presentation
Localization...
Results
Global concepts
SFT represents an uncommon type of neoplasm with mesenchymal origin,
accounting for approximately 1%-2% of all tumours located in soft tissues.
Initially,
it was believed to affect exclusively the pleura,
however,
in the recent years,
numerous cases with extrapleural localization have been described,
rising to approximately 40% of all cases [1],
involving practically every organ system.
Histologically,
SFT is composed of a fusocellular proliferation (fibroblasts,
myofibroblastst),
admixed with an extracellular hyaline matrix and vascularization.
Different subtypes according to the dominating component are described,...
Conclusion
The finding of a well defined solid lesion,
hypervascular with prominent perilesional vessels,
and located in depth proximally at extremities and in the abdominal cavity,
suggest the diagnosis of soft tissue SFT.
Imaging studies are useful in a pre-surgical approach and in surveillance.
Some radiological characteristics such as signal intensity and tumor size,
are predictable of a more aggressive behavior.
In addition,
our study discloses a slight predilection for superficial location in tumors with malignant pathological features,
compared to those with benign histology.
References
1. 1.
Francis N.
Musyoki & Ayoub Nahal & Thomas I.
Powell.
Solitary fibrous tumor: an update on the spectrum of extrapleural manifestations.
Skeletal Radiology (2012) 41:5 – 13.
2. 2.
Fletcher CDM,
Bridge JA,
Lee JC.
Extrapleural solitary fibrous tumor.
Who Classification of Tumours of Soft Tissue and Bone,
Editors: Fletcher CDM,
Brdige JA,
Hogendoorn PCW I Mertens F.
World Health Organization (WHO) Press,
Lyon,
França
3.3.
Alampady K.
Shanbhogue,
MD,
Srinivasa R.
Prasad,
MD, Naoki · Takahashi,
MD, Raghunandan Vikram,
MBBS,
MRCP,
FRCR,...