Aims and objectives
Yearly 239000 new cases and 152000 deaths from ovarian cancer (OC) are registered worldwide.
OC is the 7th most common cancer and the 8th cause of women death from cancer.
5 years survival reaches 20%.
However less than 30% of women with OCare diagnosed at the stage I (although 90% of these will survive up to 5 years) [1].
An important reason of high mortality rates of patients with OC is the identification of the lesion at stage III and/or IV.
This is dependent on...
Methods and materials
This study included 16 patients with BOT and 34 patients with malignant ones and 16 women without any diagnosed ovarian pathology (control group) – total 66 patients (age range,
23 - 83 years; mean,
55 years).
From December 2017 to September 2018 all patients were examined at the National Medical Research Centre of Oncology (Moscow,
Russia).
All tumors were histologically verified.
The histopathological types of OT in examined patients areshown at the Table 1.
For all patientsT1WI,
T2WI,
DWI and DCE-MRI were obtained by Magnetom...
Results
Women of BOT group had: curves of type I and in 66.7% (10 cases) (Fig.
3),
type II - 28.6% (5 patients),
type III - 4.8% (1 case).
At the group with MOT 75.6% (23 cases) (Fig.
4) had type III and 24.4% (11) - type II curves.
There was not TIC of type I in patients with MOT.
In our study 5 patients with borderline tumors obtained type II of TIC (Fig.
5),
but those tumors were excluded from our studybecause of limited numbers...
Conclusion
Semi-quantitative DCE-MRI is useful for differential diagnosis between benign and malignant ovarian tumors.Curve type III was specific for MOT and type I - for BOT.
IAUC60ratio was the most accurate criteria of TIC for distinguishing among BOT and MOT.
References
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Bernardin L,
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