Keywords:
Cardiac, MR, Biopsy, Contrast agent-other, Diagnostic procedure, Inflammation
Authors:
E. Gupalo, O. Stukalova, N. Mironova, T. Malkina, P. Chumachenko, S. K. Ternovoy; Moscow/RU
Results
In pts with CD the most frequent CMR phenomenon was EGE detected in 10 (33.3%) pts in 3-10 segments.
ME was detected in 6 (20%) pts in 2-7 segments.
None of CD pts revealed LGE at CMR.
4 (13.3%) pts had both EGE and ME which matched topographically in ventricular septum (Figure 2 A,B).
The most frequent finding in these pts was LGE – in 12 pts (48%),
ME was found in 10 pts (40%),
sighs of EGE in 7 pts (28%).
CMR proved the diagnosis of myocarditis only in 8 (32 %) of DCMP pts (≥2 criteria).
The sensitivity of CMR in detecting myocardial inflammation in our DCMP patients turned out to be 50%,
the specificity 100%/
Table 2.
CMR results
|
CD pts
(n= 30)
|
DCMP pts
(n = 25)
|
Р
|
ME positive pts – n (%)
|
6 (20)
|
10 (40)
|
0,19
|
Number of ME positive LV segments
|
2-7
|
3-11
|
-
|
EGE positive pts – n (%)
|
10 (33,3)
|
7 (28)
|
0,94
|
Number of EGE positive LV segments
|
3-10
|
3-17
|
-
|
LGE positive pts – n (%)
|
2 (7,4)
|
12 (48)
|
0,01
|
Number of LGE positive LV segments
|
0
|
2-17
|
-
|
Volume of LGE affected myocardium,
(sm3).
|
0
|
22,8[16,95;51,1]
|
-
|
Percent of LGE affected myocardium
|
0
|
26,6[12,3;41,7]
|
-
|
Pts with positive LLC – n (%)
|
4 (13,3)
|
8 (32)
|
0,29
|
The special evaluation of LGE-positive and LGE-negative DCMP pts revealed that LGE-positive DCMP pts were characterized by increased number of ventricular premature complexes (3643 [255;8500] vs 1091[64;2403],
p=0.04) (Figure 3).